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Author:   Fumio Hanaoka ,  Kaoru Sugasawa
Publisher:   Springer Verlag, Japan
Imprint:   Springer Verlag, Japan
Edition:   Softcover reprint of the original 1st ed. 2016
Weight:   1.154kg
ISBN:  

9784431567172

ISBN 10:   4431567178
Pages:   555
Publication Date:   31 March 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Part 1 DNA Replication.- 1 Molecular Mechanism of DNA Replication.- 2 Characteristics of Metazoan DNA Replication Origins.- 3 DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication.- Part 2 DNA Recombination.- 4 Mechanism of Homologous Recombination.- 5 Regulation of Recombination by Chromatin.- 6 Homologous Recombination During Meiosis.- Part 3 DNA Repair.- 7 DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair.- 8 The Fanconi Anemia Pathway and Interstrand Crosslink Repair.- 9 The Crossroads of Ubiquitination and DNA Repair: A Structural Perspective.- Part 4 Genome Instability and Mutagenesis.- 10 Genome Instability of Repetitive Sequence: Lesson From the Ribosomal RNA Gene Repeat.- 11 Translesion DNA Synthesis and Damage Tolerance Pathways.- 12 Mismatch Repair.- 13 Non-Homologous End-Joining.- Part 5 Chromosome Dynamics and Functions.- 14 Centromeric Chromatin and Kinetochore Assembly in Vertebrate Cells.- 15 CST Complex and Telomere Maintenance.- Part 6 Cell Cycle and Checkpoints.- 16 Signaling of DNA Replication Stress Through the ATR Checkpoint.- 17 Spindle Assembly Checkpoint: Its Control and Aberration.- 18 Molecular Insights Into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer.- Part 7 Interplay with Transcription and Epigenetic Regulation.- 19 DNA Replication and Histone M odification.- 20 Establishment and Maintenance of DNA Methylation.- 21 Active DNA Demethylation in Development, Human Disease, and Cancer.- BM Index.

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