Difficult to Treat Depression: A Carlat Guide

Author:   Chris Aiken
Publisher:   Carlat Publishing, LLC
ISBN:  

9798999881816


Pages:   348
Publication Date:   10 November 2025
Format:   Paperback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Difficult to Treat Depression: A Carlat Guide


Overview

When Your Clinical Expertise Meets Complex Cases Treatment-resistant depression challenges even the most experienced clinicians. When patients don't respond to first- and second-line treatments, the path forward requires sophisticated clinical reasoning, familiarity with advanced interventions, and a systematic approach to complex case management. This 348-page practical resource bridges the gap between research literature and clinical application, offering experienced psychiatrists a structured approach to patients who haven't responded to conventional treatments. Effective tools for your most challenging cases. Inside this book, you'll find: ✔ A comprehensive framework for evaluating and defining treatment resistance, including diagnostic reconsideration and comorbidity assessment ✔ Evidence-based strategies for optimizing pharmacotherapy: augmentation, combination, and switching protocols backed by current research ✔ Practical guidance on advanced somatic treatments including ECT, TMS, ketamine/ esketamine, and emerging neuromodulation therapies ✔ Integration of psychotherapeutic approaches for treatment-resistant populations ✔ How to identify and address contributing factors: medical comorbidities, substance use, trauma, and medication interactions ✔ Pharmacogenomic testing and personalized medicine approaches: when to use them and how to interpret results ✔ Case studies illustrating decision-making in complex clinical scenarios ✔ Strategies for maintaining therapeutic alliance and managing patient and family expectations through prolonged treatment courses ✔ Updates on pipeline treatments and future directions in the field

Full Product Details

Author:   Chris Aiken
Publisher:   Carlat Publishing, LLC
Imprint:   Carlat Publishing, LLC
Dimensions:   Width: 15.20cm , Height: 2.40cm , Length: 22.90cm
Weight:   0.626kg
ISBN:  

9798999881816


Pages:   348
Publication Date:   10 November 2025
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Reviews

""A clear and concise survey of practical approaches to resistant depression, including both psychotherapy and medications, for busy clinicians."" -Conrad Swartz, MD, PhD, Professor Emeritus, Southern Illinois University, and author of Psychotic Depression


Author Information

Dr. Aiken is the Editor in Chief of The Carlat Psychiatry Report; director of the Mood Treatment Center in North Carolina, where he maintains a private practice combining medication and therapy along with evidence-based complementary and alternative treatments; and Assistant Professor NYU Langone Department of Psychiatry. He has worked as a research assistant at the NIMH and a sub-investigator on clinical trials, and conducts research on a shoestring budget out of his private practice.

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