Overview

Aimed at the pathologist specifically, this volume and its companion book bring together a broad spectrum of protocols relevant to the routine molecular analysis of pathological samples. It is written at a level which assumes little previous knowledge of the subject as many people working in clinical pathology laboratories have only limited experience of molecular techniques. Topics in Volume One include those methods which relate to morphological analysis, such as immunocytochemistry, ""in situ"" hybridization, chromosome analysis, and flow cytometry. Volume Two demonstrates additional applications of molecular techniques to clinical samples, including the use of PCR, DNA sequencing, and nucleic acid hybridization for such diverse purposes as pathogen identification and forensic studies. Expert guidance and detailed instruction on how to ensure accuracy and reliability for all the protocols is provided.

Full Product Details

Author:   C. S. Herrington ,  James O'D. McGee
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   No. 106
Dimensions:   Width: 15.00cm , Height: 2.30cm , Length: 23.00cm
Weight:   0.687kg
ISBN:  

9780199632374

ISBN 10:   0199632375
Pages:   290
Publication Date:   01 November 1992
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Spiral bound
Publisher's Status:   Active
Availability:   To order  
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

"Molecular techniques in laboratory medicine, James O'D. McGee; immunochemistry for light microscopy, Andrew R. Heryet and Kevin C. Gatter; electron microscopical immunocytochemistry, Susan Van Noorden et al; principles and basic methodology of DNA/RNA detection by ""in situ"" hybridization, C. Simon Herrington and James O'D. McGee; viral gene detection by ""in situ"" hybridization, Stina M. Syrjanen; interphase cytogenetics - an approach to the detection of genetic aberrations in tumours, Anton H.N. Hopman et al; isotopic localization of cellular mRNA in clinical material using RNA probes, Q.A. Hamid; mRNA detection in clinical samples by non-isotopic ""in situ"" hybridization, Eric P.-H. Yap et al; ""in situ"" hybridization in diagnostic cytopathology, C.Simon Herrington and James O'D. McGee; nucleolar organizer regions and fibrillar centres, John Crocker; flow cytometry in clinical pathology, Richard S. Camplejohn; list of contents of Volume II."

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