Diagnostic Meta-Analysis: A Useful Tool for Clinical Decision-Making

Author:   Giuseppe Biondi-Zoccai
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2018
ISBN:  

9783319789651


Pages:   319
Publication Date:   16 August 2018
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Diagnostic Meta-Analysis: A Useful Tool for Clinical Decision-Making


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Overview

This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios. This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis.

Full Product Details

Author:   Giuseppe Biondi-Zoccai
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2018
Weight:   5.054kg
ISBN:  

9783319789651


ISBN 10:   3319789651
Pages:   319
Publication Date:   16 August 2018
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

SECTION I.-  1. Introduction to Clinical Diagnosis.- 2. The Evidence Hierarchy.- 3. Peculiarities of Diagnostic Test Accuracy Studies.- 4. Meta-analyses of Clinical Trials vs Diagnostic Test Accuracy Studies.- SECTION II.-  5. Designing the Review.- 6. Registering the review.- 7. Searching for Diagnostic Test Accuracy Studies.- 8. Abstracting Evidence.- 9. Appraising Evidence.- 10. Synthesizing Evidence.- 11. Appraising Heterogeneity.- 12. Statistical Packages and Diagnostic Meta-analysis and Their Application.- 13. Network Meta-analysis of Diagnostic Test Accuracy Studies.- 14. Transition to Intervention Meta-analysis.- 15. Updating Diagnostic Test Accuracy Systematic Reviews: Which, When and How Should They be Updated?.- SECTION III.-  16. Diagnostic Meta-Analysis: Case Study in Endocrinology.- 17. Diagnostic Meta-Analysis: Case Study in Gastroenterology.- 18. Diagnostic Meta-Analysis: Case Study in Oncology.- 19. Diagnostic Meta-analysis: Case Study in Surgery.- SECTION IV.-  20. Avenues for Further Research.- 21. Conclusion.

Reviews

In this book, the authors present pragmatic and useful summaries of the necessary steps for conducting diagnostic accuracy meta-analysis. ... This is a great addition to this field, which has lacked a comprehensive introductory book intended for beginners. While the Cochrane handbook also provides a good summary of this topic, this book reaches a broader audience. (Michihiko Goto, Doody's Book Reviews, April 12, 2019)


Author Information

Giuseppe Biondi-Zoccai is Associate Professor in Cardiology in the Department of Medico-Surgical Sciences and Biotechnologies of Sapienza University of Rome. He has got an established expertise in evidence-based cardiovascular medicine and is the founder of the Meta-analysis and Evidence-based medicine Training in Cardiology (METCARDIO) Collaboration. He has published more than 600 articles indexed in MEDLINE, including more than 200 systematic reviews, meta-analyses, or umbrella reviews, and he is the editor of the first books devoted to network meta-analyses and umbrella reviews. 

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