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OverviewNeuroscience has long been focused on understanding neural plasticity in both development and adulthood. Experimental work in this area has focused almost entirely on plasticity at excitatory synapses. A growing body of evidence suggests that plasticity at inhibitory GABAergic and glycinergic synapses is of critical importance during both development and aging. The book brings together the work of researchers investigating inhibitory plasticity at many levels of analysis and in several different preparations. This topic is of wide relevance across a number of different areas of research in neuroscience and neurology. Medical problems such as epilepsy, mental illness, drug abuse, and movement disorders can result from malfunctioning inhibitory circuits. Further, the maturation of inhibitory circuits may trigger the onset of critical periods of neural circuit plasticity, raising the possibility that such plastici periods could be reactivated for medical benefit by manipulating inhibitory circuitry. Full Product DetailsAuthor: Sarah L. PallasPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2010 ed. Dimensions: Width: 15.50cm , Height: 1.20cm , Length: 23.50cm Weight: 0.514kg ISBN: 9781441912428ISBN 10: 1441912428 Pages: 190 Publication Date: 17 December 2009 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsThe Origins and Specification of Cortical Interneurons.- Role of Spontaneous Activity in the Maturation of GABAergic Synapses in Embryonic Spinal Circuits.- Regulation of Inhibitory Synapse Function in the Developing Auditory CNS.- Developmental Plasticity of Inhibitory Receptive Field Properties in the Auditory and Visual Systems.- Postnatal Maturation and Experience-Dependent Plasticity of Inhibitory Circuits in Barrel Cortex.- GABAergic Transmission and Neuronal Network Events During Hippocampal Development.- Endocannabinoids and Inhibitory Synaptic Plasticity in Hippocampus and Cerebellum.- Interneuron Pathophysiologies: Paths to Neurodevelopmental Disorders.ReviewsFrom the reviews: For basic and clinical researchers and students in neuroscience and neurology, Pallas (neuroscience and biology, Georgia State U) brings together nine chapters that examine how inhibitory circuits are formed during development and how they are involved in plasticity of developing sensory and motor circuitry. ... The book originated in a symposium on the topic at the 2006 Society for Neuroscience meeting in Atlanta, Georgia. (SciTech Book News, June, 2010) From the reviews: For basic and clinical researchers and students in neuroscience and neurology, Pallas (neuroscience and biology, Georgia State U) brings together nine chapters that examine how inhibitory circuits are formed during development and how they are involved in plasticity of developing sensory and motor circuitry. ! The book originated in a symposium on the topic at the 2006 Society for Neuroscience meeting in Atlanta, Georgia. (SciTech Book News, June, 2010) From the reviews: For basic and clinical researchers and students in neuroscience and neurology, Pallas (neuroscience and biology, Georgia State U) brings together nine chapters that examine how inhibitory circuits are formed during development and how they are involved in plasticity of developing sensory and motor circuitry. ... The book originated in a symposium on the topic at the 2006 Society for Neuroscience meeting in Atlanta, Georgia. (SciTech Book News, June, 2010) Author InformationTab Content 6Author Website:Countries AvailableAll regions |