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OverviewIn this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence. Full Product DetailsAuthor: Alvaro Macieira-CoelhoPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of hardcover 1st ed. 2005 Volume: 40 Dimensions: Width: 15.50cm , Height: 2.00cm , Length: 23.50cm Weight: 0.415kg ISBN: 9783642064005ISBN 10: 3642064000 Pages: 254 Publication Date: 19 October 2010 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Out of stock ![]() The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsThe Hedgehog Signaling Pathway in Cancer.- Rho GTPases and Cancer.- Developmental Biology of Fibroblasts and Neoplastic Disease.- The Extracellular Matrix During Normal Development and Neoplastic Growth.- Wilms’ Tumor: Starting Off the Kidney All Over Again?.- Testicular Teratomas: Back to Pluripotent Stem Cells.- Tumor Suppressors APC and VHL: Gatekeepers of the Intestine and Kidney.- Hormonal and Stromal Regulation of Normal and Neoplastic Prostatic Growth.- Neoplastic Growth Through the Developmental Stages of the Organism.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |