Overview

This mongraph will be a reference for statisticians and epidemiologists involved in vaccine studies. It will also be of interest to policy makers in public health who will get a background in this area from the non-technical sections.

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9781461424888

Table of Contents

Reviews

From the reviews: ...The first comprehensive book on the topic of vaccine trials, their design and analysis. Given the recent interest in developing vaccines, ...the book is timely, relevant and important. The authors are in the vanguard of the statistical and epidemiology aspects of vaccine research and development, and their combined expertise covers an impressively broad range of topics. ...Useful for a diverse audience: graduate students, practicing biostatisticians, and professionals in epidemiology and infectious diseases. (Journal of Biopharmaceutical Statistics) In their recent book ... Halloran, Longini, Struchiner present many years of research on such studies much of which they have conducted. The book is aimed at three audiences: researchers specializing in vaccines and infectious diseases, those aiming to read their studies and students in related fields ... . The book includes problems at the end of each chapter along with answers ... . this is a well written and informative book. I recommend it to anyone interested in learning about vaccine studies. (Matthew C. Wiener, Technometrics, Vol. 53 (1), February, 2011) Researchers and postgraduate students in infectious disease epidemiology and biostatistics. ... useful to every practicing biostatistician and epidemiologist in the field. ... the authors have succeeded in writing an impressive overview of a complex topic. ... the book belongs to the shelf of all those interested in the analysis of infectious disease data. More generally, the book serves a useful textbook of statistics applied to real-life problems in which the balance between substantive research questions and the availability of data always remains an issue. (Kari Auranen, International Statistical Review, Vol. 78 (3), 2010) The book's main audience comprises two groups: clinical/basic scientists involved in research in vaccine studies and students/researchers in statistics/epidemiology interested in statistical methodologies for evaluating vaccination efficacy. ... reader interested in more technical details is provided with adequate references. ... Every aspiring statistical researcher and epidemiologist interested in vaccine studies should have this book on his or her shelf as an essential guide and reference for learning the subject, understanding the current state of the literature ... . (Debajyoti Sinha, Journal of the American Statistical Association, June, 2011) Any book targeting a wide audience with technical material confronts the problem of balancing rigor with accessibility. Design and Analysis of Vaccine Studies largely succeeds at this task. A cursory reading of this book will give readers an understanding of the concepts and techniques needed to successfully analyze vaccine studies ... . Halloran, Longini, and Struchiner have produced a text that can serve as a valuable resource for epidemiologists, biostatisticians, and anyone interested in the design and analysis of vaccine studies. (Derek A. T. Cummings and Justin Lessler, American Journal of Epidemiology, Vol. 174 (7), October, 2011)

From the reviews: “…The first comprehensive book on the topic of vaccine trials, their design and analysis. Given the recent interest in developing vaccines, …the book is timely, relevant and important. The authors are in the vanguard of the statistical and epidemiology aspects of vaccine research and development, and their combined expertise covers an impressively broad range of topics. …Useful for a diverse audience: graduate students, practicing biostatisticians, and professionals in epidemiology and infectious diseases.” (Journal of Biopharmaceutical Statistics) “In their recent book … Halloran, Longini, Struchiner present many years of research on such studies much of which they have conducted. The book is aimed at three audiences: researchers specializing in vaccines and infectious diseases, those aiming to read their studies and students in related fields … . The book includes problems at the end of each chapter along with answers … . this is a well written and informative book. I recommend it to anyone interested in learning about vaccine studies.” (Matthew C. Wiener, Technometrics, Vol. 53 (1), February, 2011) “Researchers and postgraduate students in infectious disease epidemiology and biostatistics. … useful to every practicing biostatistician and epidemiologist in the field. … the authors have succeeded in writing an impressive overview of a complex topic. … the book belongs to the shelf of all those interested in the analysis of infectious disease data. More generally, the book serves a useful textbook of statistics applied to real-life problems in which the balance between substantive research questions and the availability of data always remains an issue.” (Kari Auranen, International Statistical Review, Vol. 78 (3), 2010) “The book’s main audience comprises two groups: clinical/basic scientists involved in research in vaccine studies and students/researchers in statistics/epidemiology interested in statistical methodologiesfor evaluating vaccination efficacy. … reader interested in more technical details is provided with adequate references. … Every aspiring statistical researcher and epidemiologist interested in vaccine studies should have this book on his or her shelf as an essential guide and reference for learning the subject, understanding the current state of the literature … .” (Debajyoti Sinha, Journal of the American Statistical Association, June, 2011) “Any book targeting a wide audience with technical material confronts the problem of balancing rigor with accessibility. Design and Analysis of Vaccine Studies largely succeeds at this task. A cursory reading of this book will give readers an understanding of the concepts and techniques needed to successfully analyze vaccine studies … . Halloran, Longini, and Struchiner have produced a text that can serve as a valuable resource for epidemiologists, biostatisticians, and anyone interested in the design and analysis of vaccine studies.” (Derek A. T. Cummings and Justin Lessler, American Journal of Epidemiology, Vol. 174 (7), October, 2011)

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