Overview

The inability of cartilage tissue to self heal due to the avascular nature often leads to conditions such as osteoarthritis, traumatic rupture of cartilage and Osteochondrosis. the cartilage provides cushioning effects between joints and avoid bone frictions, the extra cellular matrix of cartilage consists predominantly of collagens, elastin, proteoglycans and glycoproteins. reconstruction of cartilage is difficult and one of the most discussed issues for researchers and clinicians of lately. until today adequate supply of cartilage replacement metrics and scaffolds with similar microenvironment of native cartilage still remain restricted. currently, numerous experiments are going on xenogeneic scaffolds and bio implants from from extracellular matrices worldwide. the decellularized tissues provide appropriate bioactive cues in the absence of cellular components, hence avoiding immunological issues.

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