Overview

The pathogenesis of both forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis, depends on complex immune abnormalities, and the investigation of cytokines has become critical to basic, clinical and therapeutic aspects of these entities. This volume offers information on the role of various immunoregulatory and pro-inflammatory mediators in Crohn's disease and ulcerative colitis. Each cytokine is analyzed in regard to pathogenic and clinical implications, taking advantage of information derived from patients and animal models, as well as immunological and molecular ""in vitro"" systems. This volume should be of interest to gastroenterologists, clinical investigators, immunologists, cell biologists and professionals interested in mucosal immunity and inflammation.

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9783540603269

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