Cytokine Molecular Biology: A Practical Approach
Author:   Fran Balkwill (Biological Therapeutics Laboratory, ICRF)
Publisher:   Oxford University Press
Edition:   2nd Revised edition
Volume:   237
ISBN:  

9780199638574


Pages:   224
Publication Date:   09 November 2000
Format:   Paperback
Availability:   Out of stock   Availability explained


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Cytokine Molecular Biology: A Practical Approach


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Overview

Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes; the detection of cytokine mRNA; receptor binding studies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written by experts in the field, this book provides a comprehensive and essential guide to cytokine research.

Full Product Details

Author:   Fran Balkwill (Biological Therapeutics Laboratory, ICRF)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Edition:   2nd Revised edition
Volume:   237
Dimensions:   Width: 18.80cm , Height: 1.30cm , Length: 24.60cm
Weight:   0.514kg
ISBN:  

9780199638574


ISBN 10:   0199638578
Pages:   224
Publication Date:   09 November 2000
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock   Availability explained

Table of Contents

Cloning and expression of cytokine genes Methods for studying cytokine gene polymorphisms Northern analysis, RT-PCR, Rnase protection, cDNA array systems and in situ hybridization detection of cytokine messenger RNA Purification, sequencing and synthesis of cytokines and chemokines Receptor binding studies Cytokine signalling Cytokine receptor signalling pathways: PC-specific phospholipase C and sphingomyelinases Proteome analysis in cytokine research Conditional and fixed cytokine gene modification in transgenic and mutant mice

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