Cytochrome P450: Structure, Mechanism, and Biochemistry

Author:   Paul R. Ortiz de Montellano
Publisher:   Springer Science+Business Media
Edition:   3rd ed. 2005
ISBN:  

9780306483240


Pages:   690
Publication Date:   21 December 2004
Replaced By:   9783319121079
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Cytochrome P450: Structure, Mechanism, and Biochemistry


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Author:   Paul R. Ortiz de Montellano
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   3rd ed. 2005
Dimensions:   Width: 17.80cm , Height: 3.90cm , Length: 25.40cm
Weight:   3.470kg
ISBN:  

9780306483240


ISBN 10:   0306483246
Pages:   690
Publication Date:   21 December 2004
Audience:   General/trade ,  General
Replaced By:   9783319121079
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Models and Mechanisms of Cytochrome P450 Action.- Computational Approaches to Cytochrome P450 Function.- Structures of Cytochrome P450 Enzymes.- Electron Transfer Partners of Cytochrome P450.- Activation of Molecular Oxygen by Cytochrome P450.- Substrate Oxidation by Cytochrome P450 Enzymes.- Inhibition of Cytochrome P450 Enzymes.- Induction of Cytochrome P450 Enzymes.- Hormonal Regulation of Liver Cytochrome P450 Enzymes.- Human Cytochrome P450 Enzymes.- Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids.- Cytochrome P450s in Plants.- The Diversity and Importance of Microbial Cytochromes P450.

Reviews

Praise for the Second Edition: Professor Paul R. Ortiz de Montellano (known in some databases as 'P.R.O. Demontellano' has spared no effort in the preparation of this major work. All 15 chapters and the two appendices were written by experts of high international reputation. The content is structured into four parts arranged clearly and logically. As a result, the reader goes from the table of contents to the main body of the book with a favourable impression of clarity and comprehensiveness. Needless to say, this impression is verified throughout the chapters.' ISSX: International Society for Study of Xenobiotics (October 1996) The 1986 edition of Cytochrome P450: Structure, Mechanism, and Biochemistry is probably the most frequently cited single source of information about the subject...Ortiz de Montellano has now produced a second edition with 15 new chapters. In my estimation, he has again succeeded in bringing the P450 field into sharp focus.' Science, 271 (March 1996)


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