Cyclic β-Glucans from Microorganisms: Production, Properties and Applications

Author:   Geetha Venkatachalam ,  Sathyanarayana Gummadi ,  Mukesh Doble
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2013 ed.
Volume:   0
ISBN:  

9783642329944


Pages:   90
Publication Date:   06 October 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Cyclic β-Glucans from Microorganisms: Production, Properties and Applications


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Overview

to Cyclic glucans are polysaccharides that are predominantly produced by Agrobacterium, Bradyrhizobium and Rhizobium sp. and widely used in the pharmaceutical and food industries. In this book, the applications, properties, analytical tools, production and genes of four main cyclic β-glucans from microorganisms are highlighted and critically evaluated. As biocompatible and biodegradable renewable resources, they have an immense potential for future applications, which has not yet been fully exploited. This concise review will help to bridge this gap.

Full Product Details

Author:   Geetha Venkatachalam ,  Sathyanarayana Gummadi ,  Mukesh Doble
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2013 ed.
Volume:   0
Dimensions:   Width: 15.50cm , Height: 0.50cm , Length: 23.50cm
Weight:   1.708kg
ISBN:  

9783642329944


ISBN 10:   3642329942
Pages:   90
Publication Date:   06 October 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Introduction 1.1. History of polysaccharides from bacteria 1.2. Cyclic ss-glucans 1.3. -cyclic glucan 1.4. Linear glucans 1.5. Cyclodextrins 2. Applications of cyclic ss-glucans 2.1. In food 2.2. Medical technology 2.3. As wound dressing material 2.4. Microparticulate form of ss-glucan for pharmaceutical application 2.5. Synthesis of selenium nanowires 2.6. Drug delivery 2.7. Enantiomeric seperator 2.8. In chiral technology 2.9. Chiral Stationary Phase 2.10. Carboxymethylated cyclic- ss-glucans as enantiomeric separators 2.11. Inclusion complexes 2.12. ss-D-Glucans complexation with Zearalenone 2.13. Inclusion complex with Paclitaxel 2.14. Inclusion complexation with a plant flavonoid luteolin 2.15. Inclusion complexation with naproxen 2.16. Functionalized ss-1, 3-Glucan in carbon nanotube 2.17. Application of cyclic ss-(1, 3),(1, 6)-glucans in chiral technology 3. Properties of cyclic glucans 3.1. Structure 3.2. Molecular biological function of ss-Glucans in immunity 3.2.1 The ss-Glucan receptor - Dectin-1 3.3. Complex forming ability 3.4. Cytotoxicity of cyclic ss-glucan 4. Analytical tools for the characterization cyclic ss-glucan 4.1. Silica gel thin-layer chromatography (TLC) 4.2. Degree of polymerization 4.3. Compositional analysis of periplasmic glucan 4.4. Glycosidic - linkage analysis 4.5. Arrangement of linkages 4.6. Protons and carbons in glucan 4.7. Molecular weight 4.8. Functional groups in cyclic ss-glucans 4.9. Supramolecular structure 4.10. Separation of mixture of cyclic-ss- glucan in HPLC 4.11. CHN analysis 5. Production of Cyclic ss-glucans 5.1. Osmolarity condition 5.2. Media details 5.3. Optimization of medium with mannitol 5.4. Effect of media components and operating conditions 5.4.1. Carbon 5.4.2. Nitrogen 5.4.3. Temperature 5.4.4. Salt and pH 6. Extraction and purification of cyclic ss- glucan 6.1. Extraction of cyclic ss- glucan from culture filtrate 6.2. Isolation and purification of osmoregulated periplasmic glucans 6.3. Isolation and purification of algal cyclic glucans 6.4. Purification of cyclic glucan from yeast 6.5. Purification using column chromatography 7. Mechanism of cyclic ss-glucans production 7.1. Genes responsible for synthesis of cyclic ss-(1, 2)-glucan in Rhizobiaceae and Agrobacteriaceae 7. 1.2. Genes for cyclic ss-(1,3) 7. 1.3. Genes for cyclic ss-(1,3)-(1,6)-glucan 7. 1. 4. Genes for cyclic ss-(1,6)-(1,3)-glucan 7. 2. Genes of periplasmic glucans (PGs) of the Proteobacteria 7.3. Metabolic pathway of carbohydrate metabolism 7.4. Enzymes involved in Cyclic ss- (1,2)-glucan synthesis 7.4.1. Cyclic ss-glucan synthase (Cssgs) 7.4.2. ss- (1, 3), ss-(1,6)-(1,3) and ss-(1,3)-(1,6) glucosyltransferase 7.4.3. Enzymes involved in ss-glucan degradation 8. Conclusions

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