Current Topics in Clinical Radiobiology of Tumors
Author:   Hans-Peter Beck-Bornholdt ,  K. Kian Ang ,  L. W. Brady ,  H. -P. Heilmann
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:  

9783540565123


Pages:   152
Publication Date:   04 November 1993
Format:   Hardback
Availability:   Out of stock   Availability explained
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Current Topics in Clinical Radiobiology of Tumors


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Overview

This provides an update of topics that at present constitute the main controversies in the field of clinical radiobiology. A critical appraisal is given of the clinical results obtained so far by the application of hyperfractionation and accelerated fractionation. In addition, the possibilities and limitations of the methods for evaluation of nonrandomized clinical studies to derive time-dose relationships for human tumours, the use of the BUDR technique for determination of tumour proliferation characteristics, the validity of the linear-quadratic model at low doses per fraction, the predictive value of SF2 for the outcome of radiotherapy, and methods for the identification of hypoxic cells are critically reviewed.

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Author:   Hans-Peter Beck-Bornholdt ,  K. Kian Ang ,  L. W. Brady ,  H. -P. Heilmann
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Weight:   0.660kg
ISBN:  

9783540565123


ISBN 10:   3540565124
Pages:   152
Publication Date:   04 November 1993
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

1 Accelerated Fractionation.- 2 Time-Dose Relationships for Human Tumors: Estimation from Nonrandomized Studies.- 3 Limitations of the Bromodeoxyuridine Technique for Measurement of Tumour Proliferation.- 4 Hyperfractionation.- 5 The Limitation of the Linear-Quadratic Model at Low Doses per Fraction.- 6 The influence of the Size of Dose on the Repair Kinetics of X-ray-Induced DNA Strand Breaks Studied in CHO Cells.- 7 The Fractionation Sensitivity of Malignant Melanomas.- 8 Radiosensitivity of Tumor Cells: The Predictive Value of SF2.- 9 Hypoxia in Tumours: Its Relevance, Identification, and Modification.- 10 The Impact of Local Tumor Control on the Outcome in Human Cancer.- 11 Cell Loss in Irradiated Tumours.- List of Contributors.

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