COX-2 Inhibitors

Author:   Michel Pairet ,  Joanne van Ryn
Publisher:   Birkhauser Verlag AG
Edition:   Softcover reprint of the original 1st ed. 2004
ISBN:  

9783034896078


Pages:   250
Publication Date:   05 November 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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COX-2 Inhibitors


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Overview

COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

Full Product Details

Author:   Michel Pairet ,  Joanne van Ryn
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   Softcover reprint of the original 1st ed. 2004
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.409kg
ISBN:  

9783034896078


ISBN 10:   3034896077
Pages:   250
Publication Date:   05 November 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The discovery of COX-2.- Structural diversity of selective COX-2 inhibitors.- The molecular and biological basis for COX-2 selectivity.- Pharmacology and toxicology of COX-2 inhibitors.- Efficacy and gastrointestinal safety of selective COX-2 inhibitors.- Role of COX-2 in ulcers and ulcer healing.- COX-2 and the cardiovascular system.- Effects on the kidney: role of COX-2 inhibitors.- Effects on the lungs: role of COX-2 inhibitors.- Reproduction: role of COX-2 and its inhibition.- COX-2 in cancer.

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