|
![]() |
|||
|
||||
OverviewCOX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field. Full Product DetailsAuthor: Michel Pairet , Joanne van RynPublisher: Birkhauser Verlag AG Imprint: Birkhauser Verlag AG Edition: Softcover reprint of the original 1st ed. 2004 Dimensions: Width: 15.50cm , Height: 1.40cm , Length: 23.50cm Weight: 0.409kg ISBN: 9783034896078ISBN 10: 3034896077 Pages: 250 Publication Date: 05 November 2012 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsThe discovery of COX-2.- Structural diversity of selective COX-2 inhibitors.- The molecular and biological basis for COX-2 selectivity.- Pharmacology and toxicology of COX-2 inhibitors.- Efficacy and gastrointestinal safety of selective COX-2 inhibitors.- Role of COX-2 in ulcers and ulcer healing.- COX-2 and the cardiovascular system.- Effects on the kidney: role of COX-2 inhibitors.- Effects on the lungs: role of COX-2 inhibitors.- Reproduction: role of COX-2 and its inhibition.- COX-2 in cancer.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |