Cortical Spreading Depression of Leao: From Mitochondrial Function to Brain Metabolic Score (BMS)

Author:   Avraham Mayevsky ,  Judith Sonn
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2022
ISBN:  

9783031080708


Pages:   420
Publication Date:   21 October 2023
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Cortical Spreading Depression of Leao: From Mitochondrial Function to Brain Metabolic Score (BMS)


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Author:   Avraham Mayevsky ,  Judith Sonn
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2022
Weight:   0.676kg
ISBN:  

9783031080708


ISBN 10:   303108070
Pages:   420
Publication Date:   21 October 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Aim of the book.- Basic principles and technology of nadh and multiparametric monitoring used in studying cortical spreading depression (csd).- Single point and multisite monitoring of brain nadh fluorescence under csd.- Sequence of physiological responses recorded during induced csd event.- Spontaneous development of csd related to brain pathophysiological conditions.- The effects of brain metabolic and other perturbations on the responses to induced csd.- Effects of pharmacological agents on csd.- Clinical monitoring of csd in the human brain.- CSD and the lifenlight score (lls).- Discussion and conclusions.- Index.

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"Dr. Avraham Mayevsky is a Professor Emeritus in The Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel. Dr Avraham Mayevsky's field of research since they started their Post-Doc training with Prof. Britton Chance in 1972, was Energy metabolism, including mitochondrial function in vivo, of the brain mainly and other tissues In Vivo, exposed to various pathophysiological conditions. During the 50 years of activity they were able to accomplish a large number of goals that have a very significant impact on the understanding of pathophysiological processes in the brain and other organs evaluated under In Vivo conditions. His vision was to develop experimental approaches and tools that will enable them to study various physiological processes in experimental animals and at the same time, will be ready for clinical applications. During the years Dr Mayevsky's laboratory published more than 60 papers dealing with the subject of Cortical Spreading Depression of Leao (CSD).  Dr. Judith Sonn was a part of the Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel, for 45 years and retired in 2017. After graduation, Dr Judith Sonn was a laboratory Manager in Prof. Joseph Kedem’s laboratory, which investigated the physiology of the cardiovascular system. She continued to study for the master’s degree under the supervision of Professor Kedem. The M.Sc. thesis (1979, Summa Cum Laude) was ""Oxygen Balance in the Myocardium"". This research approach helped to evaluate the myocardial oxygen balance In-Vivo which was described in about 15 articles. In 1991 Dr Judith Sonn joined Professor Avraham Mayevsky’s research team and as a Ph.D. student under his Supervision. The Doctoral dissertation (1996) was “Effect of Spreading Depression on the Interrelation Between Brain Energy Metabolism and Ion Homeostasis In-Vivo”.  During that time, they published 28 articles on the CSD subject."

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