Copolymers in the Preparation of Parenteral Drug Delivery Systems

Author:   Rossella Dorati
Publisher:   Nova Science Publishers Inc
ISBN:  

9781616686789


Pages:   90
Publication Date:   01 July 2010
Format:   Paperback
Availability:   Awaiting stock   Availability explained
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Copolymers in the Preparation of Parenteral Drug Delivery Systems


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Overview

Polyorthoesters have been the most intensively studied polymers for biomedical applications for their low immunogenicity, good biocompatibility and excellent mechanical properties. In the last decade, the synthesis of polyester-polyether block copolymers has attracted increasing attention, because they may be used in several pharmaceutical and medical applications such as sutures, implants for bone fixation, carriers in drug delivery and temporary matrix or scaffolds in tissue engineering. This book includes the last two decades when block copolymers containing PEO, hydrophilic B-blocks, and PAA or PAGA, hydrophobic A-blocks, have been widely utilised to formulate parenteral drug delivery systems for peptides and proteins, such as micro and nanoparticles, implants, micelles, hydrogels and scaffolds.

Full Product Details

Author:   Rossella Dorati
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Weight:   0.202kg
ISBN:  

9781616686789


ISBN 10:   1616686782
Pages:   90
Publication Date:   01 July 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Awaiting stock   Availability explained
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

Table of Contents

Introduction; Definition & Classification of Block Copolymers; Synthesis of Block Copolymers from PEO & Lactones; Mechanism of Copolymerization from PEO & Aactone; Physico-Chemical Properties of Block Copolymers from PEO & Lactones; Degradation of ABA Triblock Copolymers based on PEO & Polyesters; Parenteral Drug Delivery Systems Based on ABA Polymers; Overview on Sterilization Techniques for Block Copolymers; Conclusion; Index.

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