Overview

This report provides an assessment of recent developments in molecular genetics and their implications for medical practice, at present and in the immediate future. Adopting a public health approach, the report aims to help medical decision-makers and practitioners understand both the technical basis of progress and its potential to revolutionize the management of numerous diseases. Advances in the prevention and treatment of classical genetic disorders are considered together with newer opportunities opened up by knowledge that many common disorders, including coronary heart disease and certain cancers, have a genetic component. Throughout the report, a special effort is made to help planners, in developing and developed coutries alike, reap the full public health benefits of technologies that are becoming increasingly powerful, simple and easy to use. Relevant ethical, social and legal issues are also critically assessed in an effort to provide comprehensive guidance.

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