Overview

Clinical immunology is relevant to all medical disciplines and all doctors and other healthcare professionals who need a basic understanding of the subject. This is an up-to-date, short immunology textbook, which covers basic clinical and laboratory immunology for health professionals in training or in practice. It covers: * essential basic immunology * clinical immunology * laboratory investigations of immunological disorders. Suitable for medical students, nurses, physiotherapists and laboratory technicians, ""Concise Immunology for Health Professionals"" focuses on clinical problems seen in practice. It includes self-assessment questions and case histories to aid learning and understanding.

Full Product Details

Author:   Mary Keogan (Royal College of Surgeons, Ireland) ,  Eleanor M. Wallace (Beaumont Hospital, Ireland) ,  Paula O'Leary (Cork University, Ireland)
Publisher:   Taylor & Francis Ltd
Imprint:   Routledge
Dimensions:   Width: 17.40cm , Height: 2.10cm , Length: 24.60cm
Weight:   0.907kg
ISBN:  

9780415298308

ISBN 10:   041529830
Pages:   454
Publication Date:   09 March 2006
Audience:   College/higher education ,  Professional and scholarly ,  College/higher education ,  Tertiary & Higher Education ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Basic Immunology 1.1. Introduction 1.2. Overview of Defence Mechanisms 1.3 Cells and Organs of the immune system 1.4. Innate Immune responses I - Phagocytosis and NK cells 1.5. Innate Immune responses II - Complement 1.6. Innate Immune responses III - Other soluble factors 1.7. Inflammation 1.8. What the immune system recognises 1.9. How does the immune system see antigen? 1.10. Lymphocyte Maturation 1.11. Immunoglobin structure 1.12. B cell activation 1.13. Immunoglobin functions Self-assessment Questions 1.14. HLA molecules 1.15. TCR and Immune repertoire 1.16. Antigen presentation 1.17. Helper T cell activation 1.18. Cytotoxic T cells 1.19. Initiation of Immune response 1.20. Maintenance of the Immune response 1.21. Control of the Immune response 1.22. Ontogeny of the Immune response 1.23. Immune responses to infection 1.24.How organisms evade the immune system 1.25. Consequences of Immune response 1.26. Host defence against tumours 1.27. Overview of Autoimmunity 1.28. Allergy Self-assessment Questions Clinical Immunology 2.1. Hypersensitivity Diseases 2.2. Atopy 2.3. Asthma 2.4. Urticaria and Angioedema 2.5. Food allergy and intolerance 2.6 Anaphylaxis 2.7 Other types of Hypersensitivity 2.8. Immunodeficiency 2.9. Defects in antibody - mediated immunity 2.10 Defects in T cell-mediated immunity 2.11. Defects of neutrophil number/function 2.12. Defects of complement function 2.13. HIV 2.14 Autoimmunity 2.15. Autoimmune Endocrinopathies 2.16. Autoimmune Haematological disorders 2.17. Autoimmune Liver disease 2.18. Immune mediated gastrointestinal disease 2.19. Immune mediated Neurological disease 2.20. Autoimmune Skin diseases 2.21. Immune mediated renal disease 2.22. Rheumatiod disease 2.23. Connective Tissue Disease 2.24. Vasculitides 2.25. Immune mediated tissue damage 2.26. Transplantation 2.27. Bone-marrow transplantation 2.28. Solid Organ Transplantation 2.29. Lymphoid Malignances 2.30. Leukaemia and Lymphoma 2.31. Plasma Cell Diseases Self-assessment Questions Immunotechniques and Diagnostic Tests used in Clinical Immunology 3.1. Laboratory tests in the clinical immunology laboratory 3.2. Antibodies are essential tools in The clinical immunology laboratory 3.3. Detection of antibodies or antigen 3.4. Non-organ specific autoimmunity 3.5 Organ specific autoimmunity 3.6. Measurement of the Acute Phase response 3.7. Complement 3.8. Immunodeficiency 3.9. Abnormal immunoglobulins 3.10. Angioedema: C1-Inhibitor levels and function 3.11. Allergy and hypersensitivity 3.12. Transplantation 3.13. Immunophenotyping leukamias and lymphomas 3.14. Direct Immunofluorescence on Tissue Biopsies Self-assessment Questions Treatment of Immunological Disorders 4.1. Principles of Immunosuppression 4.2. Corticosteroids 4.3. Immunosuppression (I) 4.4. Immunosuppression (II) 4.5. Therapeutic antibody production 4.6. Targeted cell depletion 4.7. Other antibody therapies 4.8. Intravenous immunoglobulin Replacement 4.9. High Dose IVIg 4.10. Cytokine therapy 4.11. Vaccination 4.12. Removal of antibody - Plasmapheresis 4.13. Management of allergic reactions Self-assessment Questions

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Author Information

Royal College of Surgeons, Ireland Cork University, Ireland Department of Immunology Beaumont Hospital, Ireland

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