Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models
Author:   Aslak Tveito ,  Glenn T. Lines
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2016
Volume:   111
ISBN:  

9783319300290


Pages:   261
Publication Date:   20 April 2016
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models


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Author:   Aslak Tveito ,  Glenn T. Lines
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2016
Volume:   111
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   5.561kg
ISBN:  

9783319300290


ISBN 10:   3319300296
Pages:   261
Publication Date:   20 April 2016
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- Background: Contents and Method.- One-dimensional calcium release.- Models of open and state blockers.- Two-dimensional calcium release.- Computing theoretical drugs in the two-dimensional case.- Generalized systems.- Calcium-induced calcium release.- Numerical release for CICR.- A prototypical model of an ion channel.- Inactivated ion channels.- A simple model of the sodium channel.- Mutations affecting the mean open time.- The burst mode.- Whole sale action potentials.-  

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