Overview

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis.

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9780128143650

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Yun Zheng is Associate Professor in Bioinformatics at Kunming University of Science and Technology in China. He has been working in bioinformatics for more than 10 years, concentrating on non-coding RNAs, and has published over 30 papers in the area. He has developed novel tools for a wide-range of computational topics in non-coding RNAs, validated by influential work in the field of non-coding RNAs. Yun Zheng holds a PhD from the Nanyang Technological University in Singapore.

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