Computational Biology: A Practical Introduction to BioData Processing and Analysis with Linux, MySQL, and R

Author:   Röbbe Wünschiers
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2nd ed. 2013
ISBN:  

9783642430978


Pages:   449
Publication Date:   26 June 2015
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Computational Biology: A Practical Introduction to BioData Processing and Analysis with Linux, MySQL, and R


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Overview

This greatly expanded 2nd edition provides a practical introduction to - data processing with Linux tools and the programming languages AWK and Perl - data management with the relational database system MySQL, and - data analysis and visualization with the statistical computing environment R for students and practitioners in the life sciences. Although written for beginners, experienced researchers in areas involving bioinformatics and computational biology may benefit from numerous tips and tricks that help to process, filter and format large datasets. Learning by doing is the basic concept of this book. Worked examples illustrate how to employ data processing and analysis techniques, e.g. for - finding proteins potentially causing pathogenicity in bacteria, - supporting the significance of BLAST with homology modeling, or - detecting candidate proteins that may be redox-regulated, on the basis of their structure. All the softwaretools and datasets used are freely available. One section is devoted to explaining setup and maintenance of Linux as an operating system independent virtual machine. The author's experiences and knowledge gained from working and teaching in both academia and industry constitute the foundation for this practical approach.

Full Product Details

Author:   Röbbe Wünschiers
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2nd ed. 2013
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   7.197kg
ISBN:  

9783642430978


ISBN 10:   364243097
Pages:   449
Publication Date:   26 June 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part I Whetting Your Appetite.- 1 Introduction.- 2 Content of this Book.- Part II Computer & Operating Systems.- 3 Unix/Linux.- Part III Working with Linux.- 4 The First Touch.- 5 Working with Files.- 6 Remote Connections.- 7 Playing.- 8 Using the Shell.- 9 Installing BLAST+ and ClustalW.- 10 Shell Programming.- 11 Regular Expressions.- 12 Sed.- Part IV Programming.- 13 AWK.- 14 Perl.- 15 Other Programming Languages.- Part V Advanced Data Analysis.- 16 Relational Databases with MySQL.- 17 The Statistics Suite R.- Part VI Worked Examples.- 18 Genomic Analysis of the Pathogenicity Factors from E. coli Strain O157:H7 and EHEC Strain O104:H4.- 19 Limits of BLAST & Homology Modeling.- 20 Virtual Sequencing of pUC18c.- 21 Querying for Potential Redox-Regulated Enzymes.- Part VII Additional Material.- References.- A Supplementary Information.- Solutions.- Index.

Reviews

From the reviews of the second edition: This book aims to guide an astute pupil on the path to acquiring a practical familiarity with the UNIX command line. ... I found the book entertainingly written and well edited--increasingly rare attributes in current books on computing. ... The book is a spirited introduction to data processing on Unix, and will also be useful to driven data wranglers who are not necessarily in the biology field. (A. Squassabia, Computing Reviews, November, 2013) This work will be valuable to new computational biology/bioinformatics students who want to learn programming. ... Students can follow each chapter by working out the code on their own computers, and they can sharpen their programming skills by trying out the exercise at the end. ... The book will be a good starting point for many newcomers who have no or little idea of programming as well as a concise reference guide for students and scientists. Summing Up: Highly recommended. All academic and professional audiences. (V. Mathura, Choice, Vol. 51 (3), November, 2013)


rofessional audiences. (V. Mathura, Choice, Vol. 51 (3), November, 2013)


Author Information

Röbbe Wünschiers is Professor for Biochemistry/Molecular Biology at University of Applied Sciences Mittweida/Germany, where is teaching courses on biotechnology and bioinformatics. In 2004 he published the textbook “Computational Biology - Unix/Linux, Data Processing and Programming” with Springer. The new edition of this book will benefit from several years of teaching experience at different Universities, and his experience gathered while leading a bioinformatics team at BASF Plant Science, Germany.

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