Comprehensive Medicinal Chemistry II, Volume 5: ADME-TOX APPROACHES
Author:   Han van de Waterbeemd (AstraZeneca, Macclesfield, Cheshire, UK) ,  Bernard Testa (University Hospital Centre, Lausanne, Switzerland)
Publisher:   Elsevier Science & Technology
ISBN:  

9780080445182


Pages:   1181
Publication Date:   29 November 2006
Format:   Hardback
Availability:   Out of stock   Availability explained


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Comprehensive Medicinal Chemistry II, Volume 5: ADME-TOX APPROACHES


Overview

To be effective a drug must be Absorbed then Distributed to the site of action. It must also be Metabolised and Excreted without any measurable Toxicity (ADMET). This volume examines major ADMET issues, tools to measure these properties in vivo and in vitro and in-silico tools to predict and analyse effects. It concludes with a review of tools that can assist drug discovery in its early development stage.

Full Product Details

Author:   Han van de Waterbeemd (AstraZeneca, Macclesfield, Cheshire, UK) ,  Bernard Testa (University Hospital Centre, Lausanne, Switzerland)
Publisher:   Elsevier Science & Technology
Imprint:   Elsevier Science Ltd
Weight:   2.940kg
ISBN:  

9780080445182


ISBN 10:   0080445187
Pages:   1181
Publication Date:   29 November 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Unknown
Availability:   Out of stock   Availability explained

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