Comprehensive Enzyme Kinetics

Author:   Vladimir Leskovac
Publisher:   Springer Science+Business Media
Edition:   2003 ed.
ISBN:  

9780306467127


Pages:   438
Publication Date:   31 March 2003
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Comprehensive Enzyme Kinetics


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Author:   Vladimir Leskovac
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2003 ed.
Dimensions:   Width: 15.60cm , Height: 2.60cm , Length: 23.40cm
Weight:   1.800kg
ISBN:  

9780306467127


ISBN 10:   0306467127
Pages:   438
Publication Date:   31 March 2003
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Chemical Kinetics.- Kinetics of Monosubstrate Reactions.- Derivation of Rate Equations.- Linear Inhibition.- Hyperbolic and Parabolic Inhibition.- Enzyme Activation.- Kinetics of Rapid Equilibrium Bisubstrate Reactions.- Steady-State Kinetics of Bisubstrate Reactions.- Kinetic Analysis of Bisubstrate Mechanisms.- Substrate Inhibition and Mixed Dead-End and Product Inhibition.- Trisubstrate Mechanisms.- Cooperative and Allosteric Effects.- The pH Dependence of Enzyme Catalysis.- Effects of Temperature on Enzyme Reactions.- Isotope Exchange.- Kinetic Isotope Effects.- Statistical Analysis of Initial Rate and Binding Data.

Reviews

'As scientific attention turns in the post-genomic era, once again, to the properties of proteins, and particularly to their preeminent role as catalysts, Professor Leskovac's book, Comprehensive Enzyme Kinetics, will have to be on every shelf. It will, however, rarely find itself on the shelf, but much more in the hands of researchers who will daily deploy in the laboratory its wealth of useful information. Prepared under the eye of W.W. Cleland, the demiurge of enzyme kinetics, this magnum opus earns its title of comprehensive. The systematic organization of the volume, which somehow manages completeness in just over 400 pages, leads the reader to a target subject easily. The clarity of exposition will be as welcome to the experienced kineticist as it will be to the beginner. This volume is a singular achievement.' R.L. Schowen, Professor Emeritus Chemistry, Molecular Biosciences and Pharmaceutical Chemistry, University of Kansas 'Comprehensive Enzyme Kinetics is an excellent addition to the enzyme kinetics literature. It touches on all of the topics in the various areas of kinetics that might be of interest to the enzymologist. It will make a fine classroom reference text.' Herbert J. Fromm, Distinguished Professor, Iowa State University


As scientific attention turns in the post-genomic era, once again, to the properties of proteins, and particularly to their preeminent role as catalysts, Professor Leskovac's book, Comprehensive Enzyme Kinetics, will have to be on every shelf. It will, however, rarely find itself on the shelf, but much more in the hands of researchers who will daily deploy in the laboratory its wealth of useful information. Prepared under the eye of W.W. Cleland, the demiurge of enzyme kinetics, this magnum opus earns its title of comprehensive. The systematic organization of the volume, which somehow manages completeness in just over 400 pages, leads the reader to a target subject easily. The clarity of exposition will be as welcome to the experienced kineticist as it will be to the beginner. This volume is a singular achievement.' R.L. Schowen, Professor Emeritus Chemistry, Molecular Biosciences and Pharmaceutical Chemistry, University of Kansas Comprehensive Enzyme Kinetics is an excellent addition to the enzyme kinetics literature. It touches on all of the topics in the various areas of kinetics that might be of interest to the enzymologist. It will make a fine classroom reference text.' Herbert J. Fromm, Distinguished Professor, Iowa State University


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