Comparative Genomics: Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families
Author:   D. Sankoff ,  J.H. Nadeau
Publisher:   Springer
Edition:   2000 ed.
Volume:   1
ISBN:  

9780792365839


Pages:   557
Publication Date:   30 September 2000
Format:   Hardback
Availability:   In Print   Availability explained
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Comparative Genomics: Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families


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Overview

This study focuses on the evolving linear structure of the genome, from organelles and prokaryotes through to the multichromosomal nuclear genomes of plants and animals, based on modern genome map and sequence data. The collection brings together the diverse range of combinatorial optimization and probabilistic modeling techniques for analyzing genome rearrangements in the context of clinical cytogenetics, molecular genetics, population biology, microbial genomics, and the domesticated plant and animal genome projects. It critically compares functional and neutral conceptions of genome rearrangement and represents a concerted attack on the modeling and analytical problems associated with gene and genome duplication and with multigene families.

Full Product Details

Author:   D. Sankoff ,  J.H. Nadeau
Publisher:   Springer
Imprint:   Springer
Edition:   2000 ed.
Volume:   1
Dimensions:   Width: 15.50cm , Height: 3.10cm , Length: 23.50cm
Weight:   2.160kg
ISBN:  

9780792365839


ISBN 10:   0792365836
Pages:   557
Publication Date:   30 September 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Preface. Foreword; W.F. Doolittle. Introduction. Comparative Genomics; D. Sankoff, J.H. Nadeau. 1. Mechanisms. Cytogenetics, Molecular Genetics, Population Genetics. 2. Organelles: Mitochondria and Chloroplast. Rearrangements in Small Genomes. 3. Combinatorial Algorithms. A New Set of Problems for a New Kind of Data. 4. Prokaryotes. Genome Scrambling versus Functional Clustering. 5. Statistics. The Quantification of Comparative Mapping. 6. Nuclear Genomes. Evolutionary Inference from Comparative Mapping. 7. Gene and Genome Duplication and Multi-gene Families. How Can Duplication by Analyzed?

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