Combinatorial Computational Biology of RNA: Pseudoknots and Neutral Networks

Author:   Christian Reidys
Publisher:   Springer-Verlag New York Inc.
Edition:   2011 ed.
ISBN:  

9781489981479


Pages:   258
Publication Date:   02 September 2014
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Combinatorial Computational Biology of RNA: Pseudoknots and Neutral Networks


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Overview

In this monograph, new combinatorial and computational approaches in the study of RNA structures are presented which enhance both mathematics and computational biology. It begins with an introductory chapter, which motivates and sets the background of this research. In the following chapter, all the concepts are systematically developed. The reader will find * integration of more than forty research papers covering topics like, RSK-algorithm, reflection principle, singularity analysis and random graph theory * systematic presentation of the theory of pseudo-knotted RNA structures including their generating function, uniform generation as well as central and discrete limit theorems * computational biology of pseudo-knotted RNA structures, including dynamic programming paradigms and a new folding algorithm * analysis of neutral networks of pseudo knotted RNA structures and their random graph theory, including neutral paths, giant components and connectivity All algorithms presented are freely available through springer.com and implemented in C. A proofs section at the end contains the necessary technicalities. This book will serve graduate students and researchers in the fields of discrete mathematics, mathematical and computational biology. It is suitable as a textbook for a graduate course in mathematical and computational biology.

Full Product Details

Author:   Christian Reidys
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2011 ed.
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.415kg
ISBN:  

9781489981479


ISBN 10:   1489981470
Pages:   258
Publication Date:   02 September 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction.- Secondary Structures, Pseudoknot RNA and Beyond.- Folding Sequences into Structures.- Evolution of RNA Sequences.- Methods.- References.- Index.

Reviews

From the reviews: This book is devoted to the study of the structure of combinatorial models of the ribonucleic acid (RNA). This book can serve as an introduction to the study of combinatorial computational biology as well as a reference of known results and state of the art in this topic. (Ludovit Niepel, Zentralblatt MATH, Vol. 1207, 2011)


From the reviews: This book is devoted to the study of the structure of combinatorial models of the ribonucleic acid (RNA). ... This book can serve as an introduction to the study of combinatorial computational biology as well as a reference of known results and state of the art in this topic. (Ludovit Niepel, Zentralblatt MATH, Vol. 1207, 2011)


From the reviews: “This book is devoted to the study of the structure of combinatorial models of the ribonucleic acid (RNA). … This book can serve as an introduction to the study of combinatorial computational biology as well as a reference of known results and state of the art in this topic.” (Ludovit Niepel, Zentralblatt MATH, Vol. 1207, 2011)


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