Overview

Combinatorial Chemistry and Technology: Principles, Methods, and Applications, Second Edition provides comprehensive coverage of current combinatorial methodologies and technologies used in the design, synthesis, and screening of molecular libraries. It details the evolution of solid-phase chemistry, in vitro screening of biological activities, and others and explores the development of automation and robotics to satisfy the demand to produce in high yield and purityand to screen huge numbers of molecules. This second edition has been revised and updated to include important topics such as catalysis and biotechnology applications and includes a new chapter describing current ICS-UNIDO activities.

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9780824758370

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The authors have been quite successful in their efforts to provide a guide to scientists involved in the field of drug discovery with little-or-no knowledge of combinatorial chemistry...this overall instruction guide is a valuable companion to scientists involved in combinatorial work. ...The authors have succeeded in their endeavor by appraising several production methods, and comparing the costs for generating an entity through various research and development techniques. -Yesh P. Sachdeva, Synthesis, 2006

"""The authors have been quite successful in their efforts to provide a guide to scientists involved in the field of drug discovery with little-or-no knowledge of combinatorial chemistry…this overall instruction guide is a valuable companion to scientists involved in combinatorial work. …The authors have succeeded in their endeavor by appraising several production methods, and comparing the costs for generating an entity through various research and development techniques."" -Yesh P. Sachdeva, Synthesis, 2006"

Author Information

Stanislav Miertus, Giorgio Fassina

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