Overview

Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry and biology and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It also contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation. The use of automation and robotics is also explained. It is written at a level easily accessible to novices and will enable readers to use combinatorial techniques to the best advantage.

Full Product Details

Author:   Hicham Fenniri (H.C. Brown Laboratory of Chemistry, Purdue University)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   233
Dimensions:   Width: 19.00cm , Height: 2.90cm , Length: 24.60cm
Weight:   0.985kg
ISBN:  

9780199637546

ISBN 10:   0199637547
Pages:   508
Publication Date:   05 October 2000
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Synthesis of combinatorial libraries using the portioning-mixing procedure One-bead-one-compound combinatorial library method Synthesis and screening of positional scanning synthetic combinatorial libraries High throughput combinatorial synthesis of discrete compounds in multimilligram quantities Positionally addressable parallel synthesis on membrane supports Resins and anchors for solid phase organic synthesis Organic reactions on solid support - an overview Analytical methods in combinatorial chemistry Multi-component reactions (mcrs) of isocyanides and their chemical libraries Multi-step solution phase combinatorial synthesis Experimental techniques in fluorous synthesis Dendrimer-supported combinatorial chemistry Automated solution phase synthesis and its application in combinatorial chemistry Combinatorial discovery and optimization of electrocatalysts Combinatorial library synthesis using polymer-supported catalysts Combinatorial Approaches to chiral catalysts discovery

Reviews

<br> The book provides a concise description of the basic methods of combinatorial chemistry, supported by practical examples. In the 16...self-contained, well structured, and easily readable...chapters, leading experts in the field of combinatorial chemistry present various aspects of the subject that are related to their own areas of work....[A]n effective starting point for solving a wide range of problems...offers many new ideas and practical advice. --Angewandte Chemie International Edition<br>

The book provides a concise description of the basic methods of combinatorial chemistry, supported by practical examples. In the 16...self-contained, well structured, and easily readable...chapters, leading experts in the field of combinatorial chemistry present various aspects of the subject that are related to their own areas of work....[A]n effective starting point for solving a wide range of problems...offers many new ideas and practical advice. --Angewandte Chemie International Edition

The book provides a concise description of the basic methods of combinatorial chemistry, supported by practical examples. In the 16...self-contained, well structured, and easily readable...chapters, leading experts in the field of combinatorial chemistry present various aspects of the subject that are related to their own areas of work....[A]n effective starting point for solving a wide range of problems...offers many new ideas and practical advice. --Angewandte Chemie International Edition<br>

The book provides a concise description of the basic methods of combinatorial chemistry, supported by practical examples. In the 16...self-contained, well structured, and easily readable...chapters, leading experts in the field of combinatorial chemistry present various aspects of the subject that are related to their own areas of work....[A]n effective starting point for solving a wide range of problems...offers many new ideas and practical advice.--Angewandte Chemie International Edition

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