Clinical Use of Antibodies: Tumours, infection, infarction, rejection and in the diagnosis of AIDS

Author:   Richard P. Baum, MD ,  P. H. Cox ,  Gustav Hor ,  Gian Luigi Buraggi
Publisher:   Springer
Edition:   Softcover reprint of the original 1st ed. 1991
Volume:   19
ISBN:  

9789401055550


Pages:   185
Publication Date:   05 November 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Clinical Use of Antibodies: Tumours, infection, infarction, rejection and in the diagnosis of AIDS


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Overview

It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous site-chain theory -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the Ehrlich Era (first steps in immunology Magic Bullet concept) and the Behring Era (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124.

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Author:   Richard P. Baum, MD ,  P. H. Cox ,  Gustav Hor ,  Gian Luigi Buraggi
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 1991
Volume:   19
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   0.314kg
ISBN:  

9789401055550


ISBN 10:   9401055556
Pages:   185
Publication Date:   05 November 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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'To conclude, this is a summary of research findings in Nuclear Medicine of predominant interest to Nuclear Medicine Physicians particularly those interested in magic bullets , especially biological ones.' Australian Cancer Society 16:3 1992


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