Overview

This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Full Product Details

Author:   Shiyang Pan ,  Jinhai Tang
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2021
Weight:   2.914kg
ISBN:  

9789811610363

ISBN 10:   9811610363
Pages:   889
Publication Date:   09 July 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Part 1 Principles of Clinical Molecular Diagnostics.- 1 Molecules of Diseases and Their Detection Methods.- 2 Assay Performance Evaluation.- 3 Establishment of Biological Reference Interval.- 4 Ethics: Informed Consent, Patient Privacy.- 5 Bioinformatics.- 6 Report and Consultation.- 7 Factors Associated with Variation.- 8 Quality Control and Quality Assurance.- 9 Precision Medicine.- Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ.- 10 Molecules in Body Systems.- 11 Molecules in Signal Pathways.- 12 Endocrine and Metabolism.- 13 Immune System.- 14 Lipoproteins.- 15 Transport and Carrier Proteins.- 16 Coagulation and Fibrinolysis.- 17 Cardiovascular System.- 18 Pregnancy.- 19 Urine.- 20 Bone.- 21 Cancer.- 22 Translation Research of Novel Biomarker.- Part 3 Advanced Molecular Diagnostic Techniques.- 23 Next-generation Sequencing (NGS).- 24 Digital PCR.- 25 Biosensor.- 26 Microfluidic Chip.- 27 Liquid Biopsy.- 28 Molecular Targeted Imaging.- 29 Fluorescence in Situ Hybridization.- 30 Circulating DNA Quantification.- 31 DNA Methylation Detection Techniques.- Part 4 Disease Presentation and Clinical Laboratory Procedures.- 32 Immunological Disorders.- 33 Liver Diseases.- 34 Pancreatic Diseases.- 35 Digestive Tract Disease.- 36 Kidney Diseases.- 37 Cardiovascular Disease.- 38 Lung Disease.- 39 Blood Disorders.- 40 Endocrine and Metabolic Diseases.- 41 Neurological Disease.- 42 Reproductive Organ Cancer.- 43 Reproductive Organ Cancer.- 44 Transplant Matching.- 45 Paternity Test.

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Author Information

Editor Shiyang Pan, M.D, Ph.D., is a chief physician and the director of the Dept. of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Editor Jinhai Tang is a professor at The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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