Overview

The XIIIth International and the VIIth European Congress of Clinical Chemistry took place at the Netherlands Congress Centre in The Hague, from June 28th to July 3rd 1987. The Organizing Committee and the Scientific Committee for these combined congresses aimed to present the state-of-the-science as well as the state-of-the-art for those fields of clinical chemistry which show a strong progress and which will most probably inflict a great part of all clinical chemists. ""Clinical Chemistry, an Overview"" comprises almost all papers which were presented during the congress in 5 plenary lectures and 97 lectures during 24· symposia. The invited speakers, being experts in their fields of clinical chemistry, succeeded very well in presenting an overview over the newest developments in connection to the knowledge already known, thereby demonstrating the progress made in clinical chemistry during the last years. The Editors take great pleasure in thanking once more the members of the Scientific Committee and of the International Scientific Advisory Board in creating an excellent scientific programme for this congress. The Editors also take great pleasure in thanking all those whose afforts have made possible the publication of this book. We are most grateful to all speakers who also prepared a manuscript for publication. The Editors also appreciate the most helpful and encouraging attitude of Plenum Press Publishers Corporation.

Full Product Details

Author:   N.C. den Boer
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1989
Dimensions:   Width: 17.00cm , Height: 4.40cm , Length: 24.40cm
Weight:   1.479kg
ISBN:  

9781461280651

ISBN 10:   1461280656
Pages:   874
Publication Date:   28 September 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1.- The interaction between industry and the clinical chemist.- High resolution nuclear magnetic resonance spectroscopy in clinical chemistry and disease diagnosis.- Diagnostic related groups: the influence of refunding of cost on the organization of clinical laboratories.- The role of clinical chemistry in preventive medicine.- 2 Genes, Gene-Technology and DNA-Probes.- Recombinant DNA technology in the diagnosis of human inherited disease.- Pathogenesis and (prenatal) diagnosis of inherited diseases: Genetic heterogeneity and clinical diversity.- Molecular biology of the human aldolase isoenzyme gene family.- 3 Therapeutic Drug Monitoring and Toxicology.- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites.- Biological monitoring of exposure to toxic trace elements.- Practical applications of therapeutic drug monitoring: the impact of technological developments.- Laboratory diagnosis of acute poisoning: consequences for treatment.- 4 Biosensors and Biochips.- Biosensors for medical use.- Enzyme sensors and immunosensors.- 5 Autoimmune Endocrinological and Neurological Disorders.- Antibodies to the thyrotropin (TSH) receptor and autoimmune thyroid disease.- Predicting type I diabetes.- Antibodies to acetylcholine receptors in myasthenia gravis.- Polyglandular autoimmune syndrome and bronchial asthma.- 6 Coagulation.- Fibrinolysis.- Modulation of endothelial cell coagulant properties.- Deficiencies of protein C and protein S and thromboembolic disease.- 7 Rheumatic Diseases.- Biochemical events in the destruction of cartilage in rheumatic diseases.- New immunological aspects in the pathogenesis and diagnosis of rheumatic diseases.- New biochemical parameters in diagnosis of joint diseases.- Clinical biochemistry of gout.- 8 Ion Selective Electrodes.- Ion selective electrodes (ISE’s) in clinical chemistry.- Proposed recommendations on ion-selective electrode determinations of the substance concentration of sodium, potassium and ionized calcium in serum plasma or whole blood.- The clinical application of ionized calcium.- Sodium and potassium by ion selective electrodes. Clinical interpretation.- 9 Bedside Chemistry and Selftesting.- Clinical Biochemistry — an integrated service.- Technology assessment of near-patient testing.- Bedside chemistry.- 10 Clinical Chemical Aspects of Transplantation.- Relevant issues in clinical organ transplantation.- Biochemical aspects of transplantation.- HLA Class II antigens-significance in organ transplantation.- Cytomegalovirus infections and transplantation rejection. Prognostic outlook of organ transplant recipients through an immunological view.- 11 Enzymology.- New perspectives in clinical enzymology.- Structure and function of disease-related allelozymes.- The clinical enzymology of the complement system.- 12 Chemi- and Bioluminescence.- Luminescence immunoassays.- Luminescence methods for substrate and enzyme determinations.- Phagocyte chemiluininescence and immune cell interaction.- Phagocytosis-independent chemiluminescence.- 13 Clinical Chemical Aspects of Ageing.- The ageing process: epidemiology, theories and model systems.- Changes during ageing in immunology, proteins, enzymes and hormones.- Clinical biochemistry of connective tissue and its role in ageing.- Biochemical and histopathological examination of the skin. Tool for prediction of coronary atherosclerosis.- 14 Laboratory Management and Cost Effectiveness.- Can the quality of laboratory testing be maintained at reduced cost?.- Management and organization of clinical chemistry and laboratory diagnostics in GDR.- The organization of the National Health Service and its consequence for the clinical chemical laboratory in Sweden.- The organization of the National Health Care and its consequences on the clinical chemistry laboratory in Nigeria.- 15 Lipids.- Clinical significance of lipoprotein particles.- Metabolic and endocrine aspects of cardiovascular risk factors. Observations on lipid metabolism in two “experiments of nature” and one experiment of human culture.- 16 Flowcytometry.- Cinical flow cytometry: history and horizons.- Current and future prospects of flow cytometry in clinical haematology.- 17 Clinical Chemistry and Nutrition.- Assessment of the B-vitamin status: some biochemical and clinical aspects.- Growth factors in malnutrition.- The use of biochemical parameters to evaluate and to estimate the nutritional status of kidney patients.- Clinical biochemical parameters to be used in general as indicators of malnutrition of children in developing countries.- 18 Mass-Spectrometry.- Principles and applications of mass spectrometry in clinical chemistry.- Modern mass spectrometric techniques applied to the analysis of steroids.- Mass spectrometry and the diagnosis and study of metabolic disease.- Isotope dilution — mass spectrometry as a reference method.- 19 Quality Assurance.- Expert systems for the clinical interpretation of laboratory reports.- Quality control in clinical laboratories.- 20 Human Infertility.- Clinical aspects of female infertility.- GIFT: Basic and clinical concepts of a new treatment for infertility of various cases.- Future possibilities in reproductive medicine.- 21 Clinical Immunology.- The multichain Interleukin-2 receptor: from the gene to the bedside.- New concepts in the etiopathogenesis of systemic lupus erythematosus.- IgE-mediated hypersensitivity.- Recent advances in our knowledge of complement.- 22 Regulatory Peptides.- Gamma-endorphin with deviant biological activity: a molecular marker for schizophrenia?.- Regulatory peptides in the control of food intake.- Regulatory peptides in health and disease.- b-Endorphin and reproduction: evidence for ovarian participation.- 23 The Thyroid and Functioning Hormones.- Cellular aspects of thyroid hormones.- Methods of analysis of thyroid-related hormones.- Thyrotropin secretion in health and disease.- 24 Veterinary Clinical Chemistry.- Biochemical disorders in nonhuman primates with hyperbilirubinemia.- Biochemical alterations in liver diseases of domestic animals.- Clinical chemistry in liver-toxicity testing: differences between species.- Lipid metabolism in large animals.- 25 Clinical Biochemistry in Developing Countries.- Clinical biochemistry in developing countries in Asia.- Clinical biochemistry services in tropical Africa.- Clinical biochemistry services in India.- Clinical biochemistry services in Indonesia.- Problems in clinical chemistry in developing countries: summary and possible solutions.- Author Index.

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