Click Chemistry: In Chemistry, Biology and Macromolecular Science

Author:   Floris Rutjes (Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands) ,  Valery V. Fokin (Department of Chemistry, The Scripps Research Institute, La Jolla, USA) ,  K. Barry Sharpless (The Scripps Institute, La Jolla, USA)
Publisher:   Wiley-VCH Verlag GmbH
ISBN:  

9783527320851


Pages:   400
Publication Date:   10 January 2022
Format:   Hardback
Availability:   In Print   Availability explained
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Click Chemistry: In Chemistry, Biology and Macromolecular Science


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Overview

This timely and much-needed publication highlights the advantages and limitations of the click approach, making this information available in one ""easy-to-digest"" volume. Edited by the pioneers in the field and with a list of authors reading like the ""Who's Who"" of click chemistry, the book assembles reviews from practitioners who have used this technique in their research. They span the fields of metal-catalyzed transformations, medicinal and bioorganic chemistry, materials and polymer science. Equally important for beginners and experienced researchers, this is the definite, first and only reference source for everyone working in the field. With a preface by Nobel prizewinner Barry Sharpless, the father of click chemistry.

Full Product Details

Author:   Floris Rutjes (Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands) ,  Valery V. Fokin (Department of Chemistry, The Scripps Research Institute, La Jolla, USA) ,  K. Barry Sharpless (The Scripps Institute, La Jolla, USA)
Publisher:   Wiley-VCH Verlag GmbH
Imprint:   Wiley-VCH Verlag GmbH
Dimensions:   Width: 17.00cm , Height: 17.00cm , Length: 24.00cm
ISBN:  

9783527320851


ISBN 10:   3527320857
Pages:   400
Publication Date:   10 January 2022
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction/Definition of Click Chemistry Catalytic Azide-Alkyne Cycloaddition and Related Reactions Fragment-Based Lead Discovery Using In Situ Click-Chemistry Synthesis of Biologically Relevant Compound Libraries Using Click Chemistry Applications in Supramolecular Chemistry and Synthesis Azides in Glycobiology Bioorthogonal Reactions for Bioconjugation Enabling Chemistry for Activity-Based Protein Profiling Dendrimers and Hyperbranched Polymers Via Click Chemistry Functionalized Polymers Using Click-Chemistry Surface Modification Via Click-Chemistry Responsive Polymeric Materials

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Author Information

Valery V. Fokin received his Ph.D. degree in 1998 from the University of Southern California, where he worked under the direction of Prof. Nicos A. Petasis. He then joined the group of Nobel Prize Winner Prof. K. Barry Sharpless at The Scripps Research Institute in La Jolla, California as a postdoctoral fellow, where he studied catalytic oxidations of olefins. In 2000, he was appointed assistant, and in 2006 associate professor in the Chemistry Department at Scripps. His research is centered on understanding of the chemical reactivity and its applications in chemistry, biology, and materials science. Floris P.J.T. Rutjes received his PhD with Professor Nico Speckamp in 1993. After a post-doctoral stay in the group of Professor K. C. Nicolaou (The Scripps Research Institute, La Jolla, USA), he was appointed at the University of Amsterdam in 1995. Four years later, he became full professor in synthetic organic chemistry at the University of Nijmegen. In 2002, he was awarded the GoldMedal of the Royal Netherlands Chemical Society (KNCV) and in 2003 the AstraZeneca award for research in organic chemistry. His research interests include the use of bio- and metal-catalysts in organic synthesis and the development of novel synthetic methodology.

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