Overview

Chondrosarcoma, a rare cancer that develops from cartilage cells, occurs mainly in the bones but can also appear in the soft tissue of the pelvis, hip and shoulder. Unfortunately, these cancers are highly resistant to both chemotherapy and radiation, and no successful adjuvant therapies currently exist. As such, surgical treatment and resection remain the mainstays of management for patients with these tumors. This concise text is a comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas. Part I discusses pathology, molecular biology and imaging features of chondrosarcomas. The different types of skeletal and extraskeletal tumors are presented in detail in part II, including conventional and secondary tumors. Management approaches are outlined and described in part III - limb salvage surgery is the most common, and although less effective, radiation and chemotherapy are indicated in certain cases. Part IV examines the future of chondrosarcoma management and development of novel adjuvant therapies, as well as the relationship of this disease to similar types (e.g., chordoma).  Bringing together the most up-to-date information on this rare cancer, Chondrosarcoma will be a valuable resource for orthopedic oncologists, researchers and all medical professionals treating these challenging tumors. 

Full Product Details

Author:   Francis J. Hornicek
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2021
Weight:   0.454kg
ISBN:  

9783030745714

ISBN 10:   3030745716
Pages:   304
Publication Date:   18 June 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Part I. Biology of Chondrosarcoma.- Pathology of Chondrosarcoma.- Advances in the Molecular Biology of Chondrosarcoma.- Imaging Features of Chondrosarcoma.- Part II. Skeletal and Extraskeletal Chondrosarcoma.- Chondrosarcomas: Conventional and Secondary.- Primary Soft Tissue Chondrosarcoma.- Part III. Management of Chondrosarcoma.- Chondrosarcoma of the Axial Skeleton.- Chondrosarcoma of the Appendicular Skeleton.- Chondrosarcoma of the Hand.- Chondrosarcoma of the Clavicle.- Radiation Therapy for Chondrosarcoma.- Systemic Therapy for Chondrosarcoma.- Vascular Issues in Complex Surgical Resection of Chondrosarcoma.- Part IV. The Future of Chondrosarcoma Research and Treatment.- The Future of Chondrosarcoma Research and Treatment.

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Author Information

Francis John Hornicek, M.D., Ph.D. Professor and Chair Department of Orthopaedic Surgery Helga and Walter Oppenheimer Endowed Chair in Orthopaedic Oncology David Geffen School of Medicine at UCLA 10833 Le Conte Ave, 76-143 CHS Los Angeles, CA 

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