Overview

A number of clinical and epidemiological studies have shown that disorders of lipoprotein metabolism constitute one of the most important risk factors for the development of atherosclerosis and coronary heart disease. This volume examines the state of the art of lipoprotein subclass metabolism and its relation to these diseases. The authors also report on new developments concerning the role of lipoprotein recptors, macrophages and apolipoprotein E polymorphism in cholesterol homeostasis. The combination of general outline form and very specific aspects of cholesterol transport will interest those in other disciplines following developments in the field, as well as those directly involved in lipoprotein research.

Full Product Details

Author:   Armin Steinmetz ,  Hans Kaffarnik ,  Jürgen Schneider ,  H. Kaffarnik
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Dimensions:   Width: 17.00cm , Height: 0.60cm , Length: 24.40cm
Weight:   0.285kg
ISBN:  

9783540505488

ISBN 10:   3540505482
Pages:   112
Publication Date:   31 January 1989
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Regulation of Cholesterol Metabolism.- Receptors in the Regulation of Cholesterol Metabolism.- Apolipoprotein E Modulates the Metabolism of Apolipoprotein B Containing Lipoproteins by Multiple Mechanisms.- Regulation of Macrophage Cholesterol Homeostasis.- Hypercholesterolemia, LDL- and Scavenger Pathway.- Familial Combined Hyperlipidemia Workshop.- Lipoproteins and Atherosclerosis: Lessons from an Animal Model for Familial Hypercholesterolemia.- Use of RFLPs of the LDL Receptor Gene in Diagnosis of Familial Hypercholesterolaemia.- Lipoprotein Lp (a) Structure and Metabolism.- Genetic Polymorphism of Lipoprotein (a).- Binding Sites for Modified Low-Density Lipoprotein on Macrophagocytic Cells: Implications for Atherogenesis?.- Removal of Low-Density Lipoproteins by Alternative Pathways.- Reverse Cholesterol Transport.- Reverse Cholesterol Transport.- Antiatherogenic Effect of Apolipoprotein A-I Containing Lipoproteins.- An Apo A-I Protein a Hybrid Used for the Study of HDL Receptor Binding and Endocytosis.- Lipid Transfer Protein: Hyperalphalipoproteinemia and Cholesteryl Ester Transfer/Exchange Activity.- Role of Apolipoprotein A-IV in Reverse Cholesterol Transport.

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