Overview

Polyclonal antibodies, widely used in research and diagnostics, are conventionally isolated from the blood of immunised mammals. The fact that antibodies can also be detected in the yolk of eggs laid by immunised hens, led to the development of the yolk antibody technology as an alternative method less stressful to animals. Hens can be kept under nearly natural conditions and antibodies be isolated from the eggs. Further, the IgY-technology has the advantage that avian antibodies can be produced against several antigens which do not induce a immune response in mammals. Protocols on how to keep and immunise hens and on the extraction, isolation and use of antibodies from yolk are described in detail in this manual. For their work on yolk antibodies the authors received the FISEA (International Foundation for the Substitution of Animal Experimentation, Luxembourg) prize in 1997.

Full Product Details

Author:   Ruediger Schade ,  etc. ,  Reudiger Schade ,  Ingrid Behn
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Dimensions:   Width: 16.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   0.522kg
ISBN:  

9783540666790

ISBN 10:   3540666796
Pages:   267
Publication Date:   04 September 2000
Audience:   College/higher education ,  General/trade ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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