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Author:   Tracy Handel (Skaggs School of Pharmacy and Pharmaceutical Sciences and Department of Pharmacology School of Medicine, University of California, USA) ,  Damon Hamel ,  Tracy Handel (Skaggs School of Pharmacy and Pharmaceutical Sciences and Department of Pharmacology School of Medicine, University of California, USA) ,  Tracy Handel (Skaggs School of Pharmacy and Pharmaceutical Sciences and Department of Pharmacology School of Medicine, University of California, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   462nd edition
Volume:   461
Dimensions:   Width: 15.20cm , Height: 3.30cm , Length: 22.90cm
Weight:   0.920kg
ISBN:  

9780123749079

ISBN 10:   0123749077
Pages:   350
Publication Date:   22 July 2009
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

STRUCTURE AND FUNCTION 1. A Novel Chemokine-mediated In Vivo T Cell Recruitment Assay for Structure Function Studies (Andrew D. Luster and Gabriele Campanella) 2. Tyrosine sulfation of HIV-1 coreceptors and other chemokine-binding receptors (Micheal R. Farzan) 3. Lymphotactin Structural Dynamics (Brian F. Volkman) 4. Regulation of chemokines by posttranslational modifications (Paul Proost ) 5. Proteolytic Processing of Chemokines: Mass Spectrometry, Biochemistry, Neoepitope Antibody and Functional Characterization (Christopher Overall and Amanda Starr) 6. Multiple approaches to study Chemokine Receptor Homo and Heterodimerization (Mario Mellado) 7. Heterodimerization of Chemokine Receptors with Other GPCRs (Graeme Milligan and Shirley Appelbe) 8. Homo and Hetero-Oligomerization of Chemokines (Tracy Handel, Damon Hamel, Ariane Jansma) 9. Interactions of Chemokine with Glycosaminoglycans (Amanda Proudfoot) 10. Interactions of Chemokine with Glycosaminoglycans (Andreas J. Kungl) 11. Structures of Chemokine:Chemokine Binding Protein Complexes (Daved Fremont) 12. Activation Mechanisms of Chemokine Receptors (Mette Rosenkilde) 13. Modeling Small Molecule Compound Binding to Receptors (Richard Horuk, James Pease, N. Vaidehi) 14. Spectroscopic Approaches to Study Conformational Changes in GPCRs (David Farrens) 15. Plasmon Resonance Methods in GPCR Signaling (Victor Hruby, Isabel Alves, Gordon Tollin) 16. Flow Cytometric Analyses of GPCR Interactions or Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics (Larry Sklar) 17. Expression and Functional Reconstitution of CCR1 (Tracy Handel and Samantha Allen, Damon Hamel) 18. Characterization of the Interactions of Chemokines with Glycosaminoglycans by Fourier Transform Ion Cyclotron Resonance (Julie A. Leary) CHEMOKINE FUNCTION IN CELL MIGRATION 19. In vitro assays for studying chemokine-triggered lymphocyte transendothelial migration under physiological flow conditions (Ronen Alon and Francis Lin) 20. Microfluidic device (Eugene Butcher) 21. Two-photon imaging and quantitative analysis of leukocyte migration in vivo (Mark Miller and Jenna Cash) 22. Zymosan induced peritonitis as a model for studying chemokines and inflammatory mediators in vivo (David Greaves)

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Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences and Department of Pharmacology, School of Medicine, University of California, USA

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