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Author:   Paul Lloyd-Williams ,  Fernando Albericio ,  Ernest Giralt ,  Ernest Giralt (Biomedical Research Institute, Barcelona, Spain)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   10
Dimensions:   Width: 15.60cm , Height: 1.70cm , Length: 23.40cm
Weight:   0.710kg
ISBN:  

9780849391422

ISBN 10:   0849391423
Pages:   294
Publication Date:   23 April 1997
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

IntroductionAmino Acids and Peptide and Protein StructureAmino Acid Activation and CouplingProtection Schemes for Peptide SynthesisThe Synthesis of PeptidesSolid-Phase Peptide SynthesisThe Solid SupportProtection SchemesAttachment of the First Amino Acid to the Solid SupportChain ElongationCleavage of the Peptide from the ResinExamples of Protein Synthesis by Linear SPPSPeptide Synthesis in SolutionStrategic ConsiderationsProtection SchemesChain ElongationFinal Removal of Protecting GroupsSpecial Approaches to the Synthesis of Peptides in SolutionExamples of Peptide Synthesis in SolutionConvergent Approaches to the Synthesis of Large Peptides and ProteinsConvergent Solid-Phase Peptide SynthesisThe Coupling of Protected Peptide Segments in SolutionCoupling of Minimally Protected Peptides in Aqueous SolutionChemical Ligation of Peptide SegmentsFormation of Disulfide BridgesPeptides with Disulfide BridgesProtection of Cysteine in Peptide SynthesisChemical Methods for the Formation of Disulfide BridgesRegioselective Disulfide Bridge FormationPeptide LibrariesMultiple Peptide Synthesis in ParallelPeptide Library TechniquesExamples of Peptide Library SynthesisiEach chapter contains References

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Paul Lloyd-Williams (Universitat de Barcelona, Barcelona, Spain), Fernando Albericio (Parc Cientific de Barcelona, Spain) and Ernest Giralt (Biomedical Research Institute, Barcelona, Spain)

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