Overview

This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.

Full Product Details

Author:   David B. Weiner (University of Pennsylvania, Philadelphia, USA) ,  William V. Williams (University of Pennsylvania School of Medicine, Philadelphia,) ,  Mannfred A. Hollinger (University of California, Davis, USA) ,  Richard M. Edwards
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   14
Dimensions:   Width: 17.80cm , Height: 1.90cm , Length: 25.40cm
Weight:   0.680kg
ISBN:  

9780849378188

ISBN 10:   0849378184
Pages:   290
Publication Date:   28 November 1994
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Section I: Chemical Approaches to Rational Drug Design 1. Design, Synthesis and Antitumor Activity of an Inhibitor of Ribonucleotide Reductase 2. The Development of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors 3. The Development of Potent Angiotensin II Receptor Antagonists Using a Novel Peptide Pharmacophore Model 4. Endothelin Structure and Development of Receptor Antagonists 5. Molecular Targeting Chemistry in Rational Drug Design Section II: Structural Approaches to Rational Drug Design 6. The Role of X-Ray Crystallography in Structure-Based Rational Drug Design 7. Biocomputational Approaches to Protein-Based Drug Design 8. Architecture and Design of Zinc Protein-Ligand Complexes 9. Design of Immunomodulatory Peptides Based on Active Site Structures

Reviews

Author Information

Weiner\, David B.; Williams\, William V.

Tab Content 6

Author Website:  

Countries Available

All regions