Overview
"This book introduces charnolophagy (CP) as energy-driven, lysosomal-dependent mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) involving free radical-induced Ca2+ dyshomeostasis, ΔΨ collapse, and ATP depletion in congenital diseases, pressure ulcers, metabolic diseases, hepatic diseases, diabetes, obesity, inflammatory diseases, musculoskeletal diseases, sarcopenia, cachexia, respiratory diseases, gastrointestinal diseases, hyperlipidemia, skin and hair diseases, pulmonary diseases, cardiovascular diseases, renal diseases, sepsis-induced multi-organ failure, reproductive diseases, inflammatory diseases, ophthalmic diseases, neurodegenerative diseases, drug addiction, aging, microbial (including COVID-19) infections, and belligerent malignancies implicated in early morbidity and mortality and disease-specific spatiotemporal, targeted, safe, and effective evidence-based personalized theranostic charnolopharmacotherapeutics to cure them. Basic DRESS and GELS principles, nanoparticles to cure chronic multidrug-resistant (MDR) diseases, antioxidants as free radical scavengers, CB antagonists, CP regulators, and CS stabilizers to curb CB molecular pathogenesis (CBMP) are described for better quality of life and longevity. Specific guidelines for environmental protection and preservation of zoological and botanical species at the verge of extinction, Triple ""I"" Hypothesis for mitochondrial quality control, and transcriptional regulation of CSexR and CSendoR to cure chronic diseases are presented. Novel CP index is introduced to evaluate MDR malignancies and other chronic diseases. WHO, CDC, FDA, NIH, policy planners, cosmetologists, trichologists, players, athletes, dancers, wrestlers, equestrians, young women, aging population, toxicologists, environmental protectionists, pharmaceutical industry, biomedical scientists, researchers, medical students, physicians, nurses, paramedical professionals, and global audience will be interested in this interesting book to prevent pandemics and raise healthcare awareness."
Full Product Details
Author: Sushil Sharma (American International school of Medicine, Guyana)
Publisher: Taylor & Francis Ltd
Imprint: CRC Press
Weight: 1.960kg
ISBN: 9780367679866
ISBN 10: 0367679868
Pages: 586
Publication Date: 25 September 2023
Audience:
College/higher education
,
Professional and scholarly
,
Postgraduate, Research & Scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: In Print
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.
Author Information
Sushil Sharma is Academic Dean, AISM, Georgetown, Guyana (Stone Mountain, Atlanta, USA). Prof. & Course Director, SJSM, Bonaire and St Vincent (2011-2017). Received Ph.D. (AIIMS, Delhi, India); Radiopharmaceutical Training (BARC, Bombay), GE, Siemens, Agilent Technologies, Cardinal Health (U.S. A), Royal Society Fellowship (U.K:1988-89); MHRC Post-Doctoral Fellowship (Canada: 1989-91), 5 Gold Medals. Research Officer (AIIMS:1979-88); Research Officer (University of Montreal:1993-94); Research Associate (McGill University:1994-95); Senior Scientific Officer (IRCM, Montreal:1995-97); Scientist-E (DRDO, Delhi:1997); Scientist (U of M, Winnipeg:1997-99); Assist. Prof.2000-04; Assoc. Prof. Director, UND School of Medicine, Grand Forks:2004-08); Assoc. Prof. Director (Methodist Hospital), Scientist (TMC, Houston: 2008-11), Conference Organizer, Discovered Charnoly Body.
