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OverviewThe use of cells for the treatment of a variety of diseases is no longer a dream. Today, blood transfusion, bone marrow transplantation, the use of ex vivo cultured skin in wound healing, and peripheral stern cell transplantation, including the ex vivo expansion of hematopoietic stern cells after high-dose chemo/radiation therapy, are routine. This high standard of knowledge and skills in cell transplantation might also re sult in tackling hitherto untreatable diseases. Organ transplantation is presently the only life-saving treatment for a variety of conditions. Important findings in cell and molecular biol ogy, the identification of hematopoietic, mesenchymal and neuronal stern cells, together with breakthroughs in the methodology for isolat ing, purifying, expanding, and storing human cells could make cellular therapy an alternative to organ transplantation in certain diseases within the next decade. Placental blood may be the source of choice in isolating naive progenitor cells for allogeneic transplantation. Immunotherapy is the most hopeful strategy to date for the treat ment of tumors resistant to chemotherapy, radiation therapy, or hor mone therapy. It includes the use of tumor-infiltrating lymphocytes, ex vivo activated memory T lymphocytes, and cell-based vaccines. Full Product DetailsAuthor: H. Wekerle (MPI for Psychiatry, Martinsried, Germany) , H. Graf , J.D. TurnerPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Volume: Vol 20 Weight: 0.365kg ISBN: 9783540630494ISBN 10: 354063049 Pages: 192 Publication Date: 19 September 1997 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Temporarily unavailable  The supplier advises that this item is temporarily unavailable. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out to you. Table of ContentsSomatic gene therapy in cancer; placental blood; recent developments in the ex-vivo manipulation; monocyte-derived cells in adoptive immunotherapy of cancer; the immunological basis for the development of tumour cell and peptide-based vaccines for treatment of patients with renal cell carcinoma; transplantation of isolated islets of langerhans as treatment of diabetes mellitus; potential use of marrow stromal cells for therapy of osteogenesis imperfecta and osteoporosis; monitoring of suicide gene therapy with positron emission tomography.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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