Overview

The use of cells for the treatment of a variety of diseases is no longer a dream. Today, blood transfusion, bone marrow transplantation, the use of ex vivo cultured skin in wound healing, and peripheral stern cell transplantation, including the ex vivo expansion of hematopoietic stern cells after high-dose chemo/radiation therapy, are routine. This high standard of knowledge and skills in cell transplantation might also re­ sult in tackling hitherto untreatable diseases. Organ transplantation is presently the only life-saving treatment for a variety of conditions. Important findings in cell and molecular biol­ ogy, the identification of hematopoietic, mesenchymal and neuronal stern cells, together with breakthroughs in the methodology for isolat­ ing, purifying, expanding, and storing human cells could make cellular therapy an alternative to organ transplantation in certain diseases within the next decade. Placental blood may be the source of choice in isolating naive progenitor cells for allogeneic transplantation. Immunotherapy is the most hopeful strategy to date for the treat­ ment of tumors resistant to chemotherapy, radiation therapy, or hor­ mone therapy. It includes the use of tumor-infiltrating lymphocytes, ex vivo activated memory T lymphocytes, and cell-based vaccines.

Full Product Details

Author:   H. Wekerle ,  H. Graf ,  J.D. Turner
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1997
Volume:   20
Dimensions:   Width: 14.80cm , Height: 1.10cm , Length: 21.00cm
Weight:   0.263kg
ISBN:  

9783662035115

ISBN 10:   3662035111
Pages:   180
Publication Date:   18 April 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Somatic Gene Therapy in Cancer.- 2 Placental Blood: New Options in Hematopoietic Stem Cell Transplantation.- 3 Recent Developments in the Ex Vivo Manipulation of Hematopoietic Cells from Bone Marrow and Blood.- 4 Monocyte-Derived Cells in Adoptive Immunotherapy of Cancer: Facts and Perspectives.- 5 The Immunological Basis for the Development of Tumor Cell- and Peptide-Based Vaccines for Treatment of Patients with Renal Cell Carcinoma.- 6 Transplantation of Isolated Islets of Langerhans as Treatment of Diabetes Mellitus.- 7 Potential Use of Marrow Stromal Cells for Therapy of Osteogenesis Imperfecta and Osteoporosis.- 8 Neuronal Modulation of the Immune Response in Nervous Tissue: Implications for Neurodegenerative and Autoimmune Diseases.- 9 Transplantation of Dopamine-Synthesizing Cells in Parkinson’s Disease: Experimental Data and Clinical Application.- 10 Repairing CNS Demyelination by Glial Cell Transplantation.- 11 Monitoring of Suicide Gene Therapy with Positron Emission Tomography.- Previous Volumes Published in this Series.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions