Overview

Transfusion Medicine is a rapidly developing field of science which increasingly needs the bridging between fundamental biomedical research and applied research - this bridging is also recognised as translational research. The field of engineering of potential cells for therapeutic application does not only cover gene therapy, but also covers the manipulation of cellular characteristics and functional capacities. Harvest, preservation and manipulation of specific cells circulating in the peripheral blood extend beyond the conventional technologies. Where the procurement of human blood cells has been the field of expertise of the conventional blood bank, this extension should be regarded as a development of the field into a new direction. This new direction needs a change in philosophy, approach and expertise where an integrated collaborative attitude with the academic world is of paramount importance. This book provides the complete gamma of aspects, both academic and blood banking, of this field of science and clinical application. It illustrates the potential possibilities and future opportunities to add new therapeutic directions to clinical medicine.

Full Product Details

Author:   C.Th. Smit Sibinga ,  L.F.M.H. de Leij
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2004 ed.
Volume:   38
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   1.140kg
ISBN:  

9781402017131

ISBN 10:   1402017138
Pages:   223
Publication Date:   31 October 2003
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Cellular Engineering and Cellular Therapies — an Overview.- Gene Therapy 2002: A New Start.- Stem Cells: Potential, Selection and Plasticity.- The Potential of Stem Cell Transplantation to Rescue the Failing Liver.- The New Regulatory Environment for Cellular Therapy Products: Challenges for Academic-Based Manufacturing Facilities.- Biological Modification of Lymphocytes on Auto- and Allo-Immune Diseases.- Cell Harvest and Purification Technology — State of the Art and Future Development.- Cell Manipulation and Engineering — State of the Art and Future Developments.- Cellular Immunotherapy — Towards Direct DC Activation for Licence to Kill.- From Research to Clinical Application — the Quality Concept.- Factors Controlling Expansion and Maturation of Haematopoietic Progenitor Cells.- Cell Processing for Gene and Cell Therapy Protocols: Limitations and Opportunities!.- State of the Art in Dendritic Cell Vaccination.- Reconstituting T Cell Immunity Following Hematopoietic Stem Cell Transplantation.- State of the Art in Gene Therapy.- New Horizons in Cellular Therapies.- Cellular Engineering and Cellular Therapies — Transfusion Medicine and the Academic World.

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