Cell-free Circulating Dna: Purification And Analysis Techniques
Author:   Kristina Warton (Univ Of New South Wales, Australia) ,  Goli Samimi (National Cancer Inst, Usa)
Publisher:   World Scientific Publishing Co Pte Ltd
ISBN:  

9789811244674


Pages:   296
Publication Date:   22 August 2022
Format:   Hardback
Availability:   In Print   Availability explained
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Cell-free Circulating Dna: Purification And Analysis Techniques


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Overview

Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.

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Author:   Kristina Warton (Univ Of New South Wales, Australia) ,  Goli Samimi (National Cancer Inst, Usa)
Publisher:   World Scientific Publishing Co Pte Ltd
Imprint:   World Scientific Publishing Co Pte Ltd
ISBN:  

9789811244674


ISBN 10:   9811244677
Pages:   296
Publication Date:   22 August 2022
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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