Cell Death: Mechanism and Disease
Author:   Hao Wu
Publisher:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 2014
ISBN:  

9781493943258


Pages:   272
Publication Date:   23 August 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Cell Death: Mechanism and Disease


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Full Product Details

Author:   Hao Wu
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 2014
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   4.336kg
ISBN:  

9781493943258


ISBN 10:   1493943251
Pages:   272
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Historical Perspective – the Seven Ages of Cell Death Research.- 2. The Intrinsic Apoptotic Pathway.- 3. Molecular Basis of Cell Death Programs in Mature T Cell Homeostasis.- 4. Bcl-2 family and their therapeutic potential.- 5. IAP proteins and their therapeutic potential.- 6. Cell Death and Cancer.- 7. The DNA damage response mediates apoptosis and tumor suppression.- 8. Neuronal Death Mechanisms in Development and Disease.- 9. The Complex Interplay Between Metabolism and Apoptosis.- 10. Programmed Necrosis/Necroptosis: An Inflammatory Form of Cell Death.- 11. Structural Perspectives on BCL-2 Family of Proteins.- 12. Structural basis of death receptor signaling.

Reviews

From the book reviews: This new book comprises reviews of primary studies that elucidate apoptotic pathways in specialized cells and suggest points of intervention for the treatment of various cancers. ... Summing Up: Highly recommended. Upper-division undergraduates through professionals. (S. K. Sommers Smith, Choice, Vol. 51 (11), August, 2014)


Author Information

Hao Wu, Ph.D., is the Asa and Patricia Springer Professor at Harvard Medical School where she is a member of the Department of Biological Chemistry and Molecular Pharmacology. She is also a Senior Investigator in the Program in Cellular and Molecular Medicine at Boston Children’s Hospital. Her research focuses on elucidating the molecular basis of signal transduction by immune receptors, including the induction of cell death pathways.

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