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According to the human study, conducted by British Pharmacological Society, it was evident that Endocannabinoid system aids in regulating vomiting and nausea in animals as well as humans.The cannabinoids are useful as an anti-emetic agent which assists in controlling the symptoms associated with vomiting and nausea.The CBD oil has promising results for treating chemotherapy-induced nausea and vomiting, especially for cancer patients.According to the studies, CBD activates 5-HT1A receptors which result in anti-nausea and anti-emetic effects.According to different studies conducted by Parker, Laimbeer, and Rock in 2011 and 1999, CBD content present in the Cannabis plant is highly effective in treating the symptoms associated with nausea and prevents anticipatory nausea which occurs in the chemotherapy patients.Nausea and vomiting are extremely common and often indicative of serious illness. Though the causes of nausea and vomiting differ with age and health conditions, the timing of their occurrence typically indicates the specific reason.For centuries, people have turned to cannabis for suppressing vomiting and nausea. According to a study published in 2012, given in small dosage, CBD appears to aide in ridding symptoms of both vomiting and nausea. The study published in the British Journal of Pharmacology identified that CBD acts in a diphasic manner successfully suppressing toxin-induced vomiting when taken in a moderate dose. In high doses, it displayed either the opposite or no reactionSubstantial evidence shows how the endocannabinoid system appears to regulate nausea and vomiting in humans and other mammals. Cannabinoids, specifically CBD, contain antiemetic (anti-nausea) properties that indirectly activate particular receptors in the midline of the brain stem. These receptors are known as the dorsal raphe nucleus. In limited doses, compounds of CBD bind to the CB1 receptor of the endocannabinoid system and produce a biological response that suppresses vomiting.

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