Overview

Millions of people are living with a silent disease they've likely never heard of.NASH, short for nonalcoholic steatohepatitis, is a type of liver disease in which liver fat builds up in people.NASH has become more common in recent years, and it's estimated to affect about 16 million Americans. It's a type of a more broad condition called non-alcoholic fatty liver disease, which affects an estimated 64 million Americans. And NASH is set to surpass hepatitis as the biggest reason for liver transplants by 2020.Right now, the only way to treat NASH is through weight loss and maintaining a healthy weight and diet. It's often called a silent disease because most people don't know they have it. NASH doesn't have many symptoms until its later stages, when it leads to problems like cirrhosis and liver failure.There's a simple reason why the disease flew under the radar for so long, Mark Pruzanski, CEO of Intercept Pharmaceuticals, a company that's focused on treatments for liver diseases including NASH, told Business Insider. It's because they didn't see it, he said.Historically, one of the leading causes of liver transplants has been cryptogenic cirrhosis, a condition that affects liver function and causes irreversible liver damage. But what caused many cases of the cryptogenic cirrhosis wasn't known until recently. It turns out most if not the vast majority of cryptogenic cirrhotics are NASH patients, Pruzanski said. But as the liver starts to get more damaged, the fat and other telltale signs of NASH start to go away. By the time the person came in needing a transplant, it was no longer clear what led to the cirrhosis, making it hard to diagnose as NASH.Research shows that cannabis cannot only alleviate pain and inflammation of the liver, it can also treat the root cause of the condition. Besides that, it also: Restores liver functionNormalizes 5-HT levelsImproves brain pathologyNAFLD is the most prevalent liver disease worldwide, according to a research report released April 2017 by University of Massachusetts on Cannabis use and NAFLD.A 2011 lab study on mice with a model of hepatic encephalopathy showed the following results: Neurological and cognitive functions were restoredDecreased motor functions were partially restoredIncreased plasma levels of ammonia, bilirubin, liver enzymes and 5-HT levels were normalizedAstrogliosis in the brains was moderated.A lab study carried out one month later concluded that CBD significantly reduced the extent of liver inflammation, oxidative/nitrative stress, cell death as well as having showed other protective effects. Yet another 2011 study reveals that cannabidiol causes the death of activated Hepatic Stellate Cells (HSCs) in liver fibrosis.To Know more about this disease and CBD Oil, get a copy of this book now!

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