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OverviewCaspases as Molecular Targets for Cancer Therapy discusses the recent developments on targeted therapies for cancer using caspases. It describes the selection of specific caspases for cancer therapy with the current standard of care and highlights numerous assay techniques for caspase activities. This book discusses topics such as mutations within apoptosis gene, inflammatory caspases, tumor suppression, and the different caspase types and their role in anticancer activity. In addition, it discusses caspase activity assay procedure and future perspectives. It is a valuable resource for researchers, students, and members of biomedical and medical fields who want to learn more about novel anticancer targeted therapies. Full Product DetailsAuthor: Ankur Vaidya, PhD (Assistant Professor, Pharmacy College, Uttar Pradesh University of Medical Sciences, India)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Weight: 0.450kg ISBN: 9780443156441ISBN 10: 0443156441 Pages: 264 Publication Date: 16 August 2024 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of Contents1. Introduction to Caspases, its function, mechanism, and classification 2. Mutations within apoptosis gene and caspases 3. Inflammatory caspases -1, -4, and -5 and their role in anticancer activity 4. Caspase-2 and tumor suppression 5. Caspase-3: A promising target for anticancer agents 6. Caspase-7 mutations and its activators 7. Re-instating the expression and activation of caspase-8 and caspase-10 in cancer therapy 8. Caspase-9 gene mutation and its activators 9. Caspases activity assay procedure 10. Current and future prospective of caspases targeting in cancer therapyReviewsAuthor InformationDr. Ankur Vaidya obtained his PhD from Dr. H.S. Gour University, when he researched design, synthesis, and screening of a few quinoline and oxadiazole derivatives for anticancer activities. He has 12 years of experience in teaching and research, and already supervised 18 PhD students. He wrote 5 book chapters and co-authored 2 books, including Nanotechnology Applications for Cancer Chemotherapy (Elsevier, 2020). Tab Content 6Author Website:Countries AvailableAll regions |