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Author:   J. F. Douglas ,  J F Douglas
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 1984
Volume:   4
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   0.545kg
ISBN:  

9781461295921

ISBN 10:   1461295920
Pages:   335
Publication Date:   12 October 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

I: The Fundamental Biology.- Section A: Mutagenesis and Other Short-Term Tests.- 1 An Overview of Short-Term Testing.- 2 Genetic Toxicology: Applications and Testing Strategies.- 3 Consequences of Genotoxic Effects.- 4 In Vitro Cell Transformation: An Overview.- 5 Lung Tumors in Mice.- 6 Tissue Genotoxic Effects.- Section B: Carcinogenesis.- 7 Basic Principles of Chemical Carcinogenesis.- 8 Pathology of Toxic, Preneoplastic, and Neoplastic Lesions.- 9 Carcinogen Bioassay Design.- 10 Evaluation and Interpretation of Carcinogenesis Bioassay Results.- II: Practical Carcinogenesis and Mutagenesis Assay Methodology.- Section A: Gene Mutation Assays.- 11 Bacterial Reverse and Forward Mutation Assays.- 12 Yeast Assays in Mutagen and Carcinogen Screening.- 13 Mouse Lymphoma Cell Assays.- 14 Chinese Hamster Ovary Mutation Assays.- 15 Drosophila Assay Systems.- Section B: DNA Damage and Repair Assays.- 16 Detection of DNA Damage and Repair in Bacteria.- 17 Mammalian DNA Repair Assays.- Section C: Cytogenetic Assays.- 18 Cytogenetic Assays: Aberrations and SCE Techniques.- Section D: Transformation Assays.- 19 In Vitro Transformation Assays Using Mouse Embryo Cell Lines: Balb/c-3T3 Cells.- 20 In Vitro Transformation Assays Using Mouse Embryo Cell Lines: C3H/10T1/2 Cells.- 21 In Vitro Transformation Assays Using Diploid Syrian Hamster Embryo Cell Strains.- Section E: Short-Term In Vivo Carcinogenesis Assays.- 22 Lung Tumor Assay.- 23 Tissue Genotoxic Effects: Methods.- Section F: Conduct of Carcinogen Bioassays.- 24 Conduct of Carcinogen Bioassays.

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