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Author:   Susan C. Frost ,  Robert McKenna
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 2014
Volume:   75
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   6.613kg
ISBN:  

9789402402506

ISBN 10:   9402402500
Pages:   430
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Preface. Part I  Introduction.- Overview of the Carbonic Anhydrase Field.- Part II Carbonic Anhydrases: Ancient but Relevant. Physiological Functions of the Alpha Class of Carbonic Anhydrases.- Catalytic Mechanism of α-Class Carbonic Anhydrases: CO2 Hydration and Proton Transfer.- Structure and Catalytic Mechanism of b-Carbonic Anhydrases.- Prokaryotic Carbonic Anhydrases of Earth’s Environment.- Carboxysomal Carbonic Anhydrases.- Carbonic Anhydrases and their Interplay with Acid/base-coupled Membrane Transporters.- Carbonic Anhydrase Related Proteins: Molecular Biology and Evolution.- Membrane Associated Carbonic Anhydrase IV (CA IV): A Personal and Historical Perspective.-  Carbonic Anhydrase Expression in Kidney and Renal Cancer: Implications for Diagnosis and Treatment.- Carbonic Anhydrase IX: Regulation and Role in Cancer.- Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases.- Carbonic Anhydrase IX (CAIX) as a Mediator of Hypoxia-induced Stress Response in Cancer Cells.- Carbonic Anhydrases and Brain pH in the Control of Neruronal Excitability.- Carbonic Anhydrase Inhibitors: Drug Design.- Natural Products that Inhibit Carbonic Anhydrases.- Glaucoma and the Application of Carbonic Anhydrase Inhibitors.- Carbonic Anhydrase Inhibitors and High Altitude Illnesses.- Thermal-Stable Carbonic Anhydrases: A Structural Overview.- Carbonic Anhydrases in Industrial Applications. Index.

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