Overview

Carbocation chemistry is not only fundamental to the advancement of organic chemistry, it also has found widespread applications in organic synthesis. It is not an exaggeration to say that carbocation chemistry is part of the foundation of organic chemistry. Carbocation Chemistry: Applications in Organic Synthesis provides a panoramic view of carbocation chemistry with an emphasis on synthetic applications. This book is an invaluable tool for organic, medicinal and analytical chemists, including those working in biochemistry as well as the petroleum, plastics and pharmaceutical industries. It is also suitable for upper level undergraduates and graduates in organic chemistry, biochemistry and medicinal chemistry.

Full Product Details

Author:   Jie Jack Li
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.410kg
ISBN:  

9780367873462

ISBN 10:   036787346
Pages:   224
Publication Date:   10 December 2019
Audience:   College/higher education ,  Postgraduate, Research & Scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Chapter 1. Introduction Nomenclature, Structure, and Stability Generation of Carbocations The Non-Classical Ion Controversy Electrophilic Addition to Alkenes Electrophilic Aromatic Substitution Elimination reactions Rearrangement Reactions of Carbocations References Chapter 2. Nucleophilic Aliphatic Substitution – SN1 Introduction -Activated Alcohols—Brønsted Acids -Activated Alcohols—Lewis Acids Alkylation of Aldehydes and Ketones Glycosylation Friedel–Crafts Alkylation and Acylation Electrophilic Fluorination Using Fluoronium Ion Miscellaneous SN1-related Reactions References Chapter 3. Nucleophilic Aliphatic Substitution – SN2 Construction of Quaternary Stereogenic Centers Sulfur Chemistry Organometallic Chemistry Macrocyclization Glycosylation Nucleoside Analogues N-Alkylation Cyclotetraphosphazenes Conformationally Locked Tetrahydropyran Ring The Ionic Liquid Effect Silver Chemistry References Chapter 4. Electrophilic Addition to Alkenes Introduction Cyclopropanation Hydroboration/Oxidation The Pauson–Khand Reaction Prins Reaction Schmidt Reaction Halogenation Oxymercuration/Reduction Epoxidation Gold-Catalyzed Alkyne Hydration Conclusion References Chapter 5. Electrophilic Aromatic Substitution Introduction Nitration Halogenation Friedel–Crafts Alkylation Friede

Reviews

Author Information

Jie Jack Li earned his Ph.D. in organic chemistry in 1995 at Indiana University. After a stint as a postdoctoral fellow at MIT, he worked as a medicinal chemist at Pfizer and Bristol-Myers Squibb from 1997 to 2012. Since then he has been an Associate Professor of Chemistry at the University of San Francisco teaching organic and medicinal chemistry. He has published 23 books ranging from organic and medicinal chemistry, to the history of drug discovery.

Tab Content 6

Author Website:  

Countries Available

All regions