Overview

Full Product Details

Author:   Natalia L. Komarova ,  Dominik Wodarz
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Edition:   2014 ed.
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   4.912kg
ISBN:  

9781461483007

ISBN 10:   146148300
Pages:   227
Publication Date:   15 November 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Background and Scope of the Book.- Part I Treatment of Cancer with Small Molecule Inhibitors.- An Introduction to Small Molecule Inhibitors and Chronic Myeloid Leukemia.- Basic Dynamics of Chronic Myeloid Leukemia During Imatinib Treatment.- Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation.- Evolutionary Dynamics of Drug Resistant Mutants in Targeted Treatment of CML.- Effect of Cellular Quiescence on the Evolution of Drug Resistance in CML.- Combination Therapies: Short term versus Long term Strategies.- Cross Resistance: Treatment and Modeling.- Mathematical Modeling of Cyclic Cancer Treatments.- Part II Treatment of Cancer with Oncolytic Viruses.- Introduction to Oncolytic Viruses.- Basic Dynamics of Oncolytic Viruses.- Mitotic Virus Transmission and Immune Responses.- Axiomatic Approaches to Oncolytic Virus Modeling.- Spatial Oncolytic Virus Dynamics.- Oncolytic Viruses and the Eradication of Drug-resistant Tumor Cells.

Reviews

From the reviews: The intended audience includes advanced undergraduate and graduate students in applied mathematics as well as in the field of biology with a special interest in oncology. It could serve as a guide to scientists and researchers in the field of oncology and therapeutics. ... This is the first in-depth study of mathematical and computational approaches used to understand cancer therapies. The crisp language, well-structured chapters, and precise examples are the highlights of this book. (Parthiv Amin, Doody's Book Reviews, March, 2014)

From the reviews: The intended audience includes advanced undergraduate and graduate students in applied mathematics as well as in the field of biology with a special interest in oncology. It could serve as a guide to scientists and researchers in the field of oncology and therapeutics. ... This is the first in-depth study of mathematical and computational approaches used to understand cancer therapies. The crisp language, well-structured chapters, and precise examples are the highlights of this book. (Parthiv Amin, Doody's Book Reviews, March, 2014)

Author Information

Natalia Komarova and Dominik Wodarz are professors at University of California, Irvine.

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